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Human Oral Keratinocytes | ||||
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| Product Name | Human Oral Keratinocytes | |||
| Price | Get Quote | |||
| Product Code | HOK | |||
| Cat.No | ABC-TC3733 | Species | Human | |
| Size/Quantity | 1 vial | Biosafety Level | 1 | |
| Shipping Info | Dry Ice | Storage | Liquid Nitrogen | |
| Description | Human Oral Keratinocytes (HOK), obtained from the lining mucosa of the human oral cavity, serve as a crucial line of defense against physical, microbial, and chemical threats in the oral environment. They actively contribute to the inflammatory response by secreting cytokines like IL-1β and IL-18, either constitutively or in response to various stimuli, potentially assisting in the management of oral infections. Furthermore, these keratinocytes display distinctive differentiation markers, with their gene transcription subject to calcium-induced alterations, showcasing their adaptability to environmental challenges. With notable structural and functional parallels to dermal keratinocytes, HOK underscore their pivotal role in maintaining oral health and regulating the immune
Why choose Human Oral Keratinocytes from AcceGen? Human Oral Keratinocytes(HOK) are cryopreserved at passage one, supplied in frozen vials with over 5×105 viable cells per vial. These cells undergo rigorous quality testing to confirm their ability to exhibit proper growth and maintain morphology for a minimum of 10 population doublings, ensuring their reliability and utility in various research applications. | |||
| Disease | Normal | |||
| Source Organ | Oral | |||
| Quality Control | All cells test negative for mycoplasma, bacteria, yeast, and fungi. | |||
| Recommended Medium And Supplement | ABM-TM3733 Human Oral Keratinocytes Medium Kit | |||
| Citation Guide | When you publish your research, please cite our product as “AcceGen Biotech Cat.# XXX-0000”. In return, we’ll give you a $100 coupon. Simply click here and submit your paper’s PubMed ID (PMID). | |||
| Application | FOR RESEARCH USE ONLY Human Oral Keratinocytes (HOK) offer a versatile serum-free culture model with a wide range of applications. They are invaluable for investigating microbial-to-epithelial cell interactions, unraveling the dynamics of growth factors, exploring wound healing mechanisms, delving into toxicology studies, and deepening our understanding of oral epithelial biology. Additionally, HOK serve as valuable tools for the examination of fundamental keratinocyte biology and the intricate processes of immortalization and malignant transformation, making them essential in both basic research and clinical contexts. | |||
| Growth Conditions | 37 ℃, 5% CO2 | |||
| Cell Type | Keratinocyte | |||
| Growth Mode | Adherent | |||
| Product Type | Oral Cells | |||
| Product Image |  | |||
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