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Immortalized Cell Lines

Immortalized Human Lung Fibroblasts

  • For research use only

Cat No.

ABI-TC155R
Product Type

Immortalized Cell Line
Cell Type

Fibroblasts/Stromal Cells
Species

Human
Growth Conditions

37 °C, 5% CO2
Source Organ

Lung
Disease

Normal
Storage

Liquid Nitrogen

Immortalized Human Lung Fibroblasts carrying the SV40T gene via lentiviral transduction, provided at 0.5 million viable cells per vial for research use.

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  • Immortalized Human Lung Fibroblasts
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Home | Immortalized Cell Lines | Immortalized Human Lung Fibroblasts

Description

Immortalized Human Lung Fibroblasts (HLFs) are derived from human lung tissue and genetically modified to enable continuous proliferation while preserving key fibroblast characteristics. These cells exhibit a typical spindle-shaped morphology, adhere to standard culture conditions, and express fibroblast markers. They retain functional properties including extracellular matrix production and responsiveness to pro-fibrotic stimuli such as TGF-β. Compared with primary lung fibroblasts, immortalized HLFs offer improved stability, reproducibility, and extended lifespan, making them a reliable in vitro model for pulmonary fibrosis, tissue remodeling, drug screening, and mechanistic studies.

Product Code

Immortalized Human Lung Fibroblasts,IHLF,Immortalized HLFs
Species

Human
Cat.No

ABI-TC155R
Product Category

Immortalized Cell Lines
Size/Quantity

1 vial
Cell Type

Fibroblasts/Stromal Cells
Growth Mode

Adherent
Shipping Info

Dry Ice
Growth Conditions

37 °C, 5% CO2
Source Organ

Lung
Disease

Normal
Biosafety Level

1
Storage

Liquid Nitrogen
Product Type

Immortalized Cell Line
Immortalization Method

SV40T
Quality Control

All cells test negative for mycoplasma, bacteria, yeast, and fungi.

Application

  • Immortalized human lung fibroblasts are widely used in pulmonary disease modeling, fibrosis research, extracellular matrix (ECM) studies, drug screening, and tumor microenvironment analysis. They respond to pro-fibrotic stimuli such as TGF-β and support mechanistic studies of cell signaling pathways. Their stable proliferation, consistent phenotype, and extended lifespan make them a reliable alternative to primary fibroblasts for reproducible, scalable, and long-term in vitro research applications.

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High Viability
To succeed in cell culture
Precision and Reliability
To support a consistent result
Customization Options
Tailed to your research

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