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Human Adrenal Cortical Cells

Product Name

Human Adrenal Cortical Cells

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Product Code

HAdCC

Cat.No

ABC-TC3477

Species

Human

Size/Quantity

1 vial

Biosafety Level

1

Shipping Info

Dry Ice

Storage

Liquid Nitrogen

Description

Human adrenal cortical cells are derived from human adrenal cortical tissue. The fetal adrenal cortex consists of two zones, the fetal and definitive adult zones, while the adult adrenal cortex comprises three distinct zones: the outer zona glomerulosa, the central zona fasciculata, and the inner zona reticularis. These cells are organized in cord-like structures that span from the adrenal capsule to the medulla, surrounded by an extensive network of capillaries. The zona glomerulosa cells are round and smaller in size compared to the polyhedral cells of the zona fasciculata, which gradually transition into the zona reticularis. The zona reticularis contains cells similar in appearance to those in the zona fasciculata, as well as a smaller cell type. Adrenocortical cells possess the ability to secrete cytokines, active peptides, and hormones. They also interact with cytokines (TNFb, IL-1, IL-6) and peptides (VIP) released by macrophages within the adrenal cortex.

 

Why choose Human Adrenal Cortical Cells from AcceGen?

AcceGen provides human adrenal cortical cells, which are cryopreserved at passage one. These cells are characterized using GFAP-specific immunofluorescence and are confirmed negative for HIV-1, HBV, HCV, mycoplasma, bacteria, yeast, and fungi. They guarantee 15 population doublings under provided culture conditions, ensuring their viability and longevity for extended research applications.

Disease

Normal

Source Organ

Adrenal

Quality Control

All cells test negative for mycoplasma, bacteria, yeast, and fungi.

Recommended Medium And Supplement
Citation Guide

When you publish your research, please cite our product as “AcceGen Biotech Cat.# XXX-0000”. In return, we’ll give you a $100 coupon. Simply click here and submit your paper’s PubMed ID (PMID).

Application

FOR RESEARCH USE ONLY

Human adrenal cortical cells have diverse applications in adrenal studies. They serve as a valuable model for investigating adrenal disorders like adrenal insufficiency, Cushing’s syndrome, Conn’s syndrome, and adrenocortical carcinoma. By studying these cells, researchers can unravel the molecular and biochemical mechanisms that control adrenal steroidogenesis. This knowledge can lead to better diagnostics and targeted therapies. Moreover, human adrenal cortical cells provide a platform to explore the effects of chemicals on adrenal hormone synthesis. Researchers can assess how various compounds impact hormone production, shedding light on the influence of external factors on adrenal function.

Growth Conditions

37 ℃, 5% CO2

Cell Type

Cortical Cell

Growth Mode

Adherent

Product Type

Adrenal Cells

Product Image AcceGen Frozen Cells & Cell Lines 1 vial
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