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Knockin Stable Cell Lines

AcceGen Knockin Stable Cell Lines

CRISPR/Cas9-induced site-specific DNA double-strand breaks (DSBs) can be repaired by homology-directed repair (HDR) or non-homologous end joining (NHEJ) pathways. Extensive efforts have been made to knock-in exogenous DNA to a specific genomic locus via the HDR pathway in mammalian cells.

As an experienced company in cell engineering, AcceGen provides reliable, affordable, and fast knock-in cell line generation service, which includes gRNA/donor DNA construction, engineered cell line generation, and PCR sequencing.

Our experienced scientists have working with various cells ranging from easy-to-transfect cell lines (tumor cell line) to hard-to-transfect cells (primary cells). So, we can provide high-quality knock-in cell lines to meet your requirements.

AcceGen knockin cell lines generation workflow

Use the Mutant Gene Nomenclature to search, if you cannot find the specific product in our database, AcceGen Custom Stable Cell Lines Service is committed to pave new ways to meet all your needs.

Cat.#NameDescriptionPrice

ABC-KH15949

Human TP53 (R273H/+) SW48 Cell Line

Human TP53 (R273H/+) SW48 Cell line is Heterozygous knockin of mutant (R273H) TP53. ...more +inquiry

ABC-KH15948

Human TP53 (R248W/+) HCT116 Cell Line

Human TP53 (R248W/+) HCT116 Cell line is Heterozygous knockin of mutant (R248W) TP53. ...more +inquiry

ABC-KH15947

Human TP53 (R248W/-) HCT116 Cell Line

Human TP53 (R248W/-) HCT116 Cell line is Knockin of mutant (R248W) TP53 and knockout of wild type al...more +inquiry

ABC-KH15946

Human TP53 (+/sil) DLD-1 Cell Line

Human TP53 (+/sil) DLD-1 Cell line is Heterozygous knockin of wild type TP53; second allele silenced...more +inquiry

ABC-KH15942

Human TP53 (-/-); PIK3CA (H1047R/+) MCF10A Cell Line

Human TP53 (-/-); PIK3CA (H1047R/+) MCF10A Cell line is Heterozygous knockin of PIK3CA kinase domain...more +inquiry

ABC-KH15938

Human TP53 (-/-); BRAF (V600K/+) MCF10A Cell Line

Human TP53 (-/-); BRAF (V600K/+) MCF10A Cell line is Homozygous deletion of TP53 exon 2 encoding the...more +inquiry

ABC-KH14782

Human STAT3 (Y705F/Y705F) DLD-1 Cell Line

Human STAT3 (Y705F/Y705F) DLD-1 Cell line is Homozygous knockin of STAT3 Y705F mutation. ...more +inquiry

ABC-KH13649

Human SF3B1 (H662Q/+) NALM-6 Cell Line

Human SF3B1 (H662Q/+) NALM-6 Cell line is Heterozygous knockin of SF3B1 mutation (H662Q). ...more +inquiry

ABC-KH12607

Human RAC1 (Q61L/+/+) SW48 Cell Line

Human RAC1 (Q61L/+/+) SW48 Cell line is Heterozygous knockin of RAC1 mutant (Q61L). ...more +inquiry

ABC-KH12606

Human RAC1 (Q61L/+) MCF10A Cell Line

Human RAC1 (Q61L/+) MCF10A Cell line is Heterozygous knockin of RAC1 mutant (Q61L). ...more +inquiry

ABC-KH11588

Human PIK3CA (H1047R/+/+/+) WiDr Cell Line

Human PIK3CA (H1047R/+/+/+) WiDr Cell line is Heterozygous knockin of PIK3CA kinase domain activatin...more +inquiry

ABC-KH11587

Human PIK3CA_x005f_x001f_ (H1047R/+) VACO 432 Cell Line

Human PIK3CA_x005f_x001f_ (H1047R/+) VACO 432 Cell line is Heterozygous knockin of PIK3CA kinase dom...more +inquiry

ABC-KH11586

Human PIK3CA_x005f_x001f_ (H1047R/+) SW48 Cell Line

Human PIK3CA_x005f_x001f_ (H1047R/+) SW48 Cell line is Heterozygous knockin of PIK3CA kinase domain ...more +inquiry

ABC-KH11585

Human PIK3CA_x005f_x001f_ (H1047R/+) MCF10A Cell Line

Human PIK3CA_x005f_x001f_ (H1047R/+) MCF10A Cell line is Heterozygous knockin of PIK3CA kinase domai...more +inquiry

ABC-KH11583

Human PIK3CA (E545K/+) SW48 Cell Line

Human PIK3CA (E545K/+) SW48 Cell line is Heterozygous knockin of PIK3CA helix domain activating muta...more +inquiry

ABC-KH11582

Human PIK3CA_x005f_x001f_ (E545K/+) MCF10A Cell Line

Human PIK3CA_x005f_x001f_ (E545K/+) MCF10A Cell line is Heterozygous knockin of PIK3CA helix domain ...more +inquiry

ABC-KH11580

Human PIK3CA_x005f_x001f_ (E542K/+) SW48 Cell Line

Human PIK3CA_x005f_x001f_ (E542K/+) SW48 Cell line is Heterozygous knockin of PIK3CA helix domain ac...more +inquiry

ABC-KH11331

Human PDGFRA (D842V/+) HCT116 Cell Line

Human PDGFRA (D842V/+) HCT116 Cell line is Heterozygous knockin of PDGFRA activating mutation (D842V...more +inquiry

ABC-KH10328

Human NRAS (Q61R/+) SW48 Cell Line

Human NRAS (Q61R/+) SW48 Cell line is Heterozygous knockin of NRAS activating mutation (Q61R). ...more +inquiry

ABC-KH10327

Human NRAS (Q61L/+) SW48 Cell Line

Human NRAS (Q61L/+) SW48 Cell line is Heterozygous knockin of NRAS activating mutation (Q61L). ...more +inquiry
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