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Primary Cells

C57BL/6 Mouse Retinal Microvascular Endothelial Cells

  • For research use only

Cat No.

ABC-TC3241
Product Type

Mouse Primary Cells
Cell Type

Endothelial
Species

C57BL/6 Mouse
Growth Conditions

37 ℃, 5% CO2
Source Organ

Retina
Disease

Normal
Storage

Liquid Nitrogen

C57BL/6 Mouse Retinal Microvascular Endothelial Cells support retinal angiogenesis research and microvascular modeling in mouse ocular studies.

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  • C57BL/6 Mouse Retinal Microvascular Endothelial Cells
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Home | Primary Cells | Animal Primary Cells | Mouse Primary cells | C57BL/6 Mouse Retinal Microvascular Endothelial Cells

Description

C57BL/6 Mouse Retinal Microvascular Endothelial Cells are isolated from the retinal capillary network of C57BL/6 mice. These cells form the vascular endothelium of the retina and are essential for maintaining the blood-retina barrier and regulating retinal blood flow. Retinal microvascular endothelial cells are involved in angiogenesis, immune privilege, and vascular permeability. Retinal endothelial cells express key markers such as CD31 (PECAM-1), VE-Cadherin, and von Willebrand factor (vWF) Avoid repeated freeze-thaw cycles in vitro to maintain cell viability and function. The cells undergo rigorous screening and isolation procedures, and are rigorously tested to ensure they are free of contamination from mycoplasma, fungi, yeast, and bacteria.

Product Code

C57BL/6 Mouse Retinal Microvascular Endothelial Cells, Mouse Retinal Microvascular Endothelial Cells, Retinal Microvascular Endothelial Cells, Microvascular Endothelial Cells, MVECs, ECs, RMVECs, C57BL/6 RMVECs
Species

C57BL/6 Mouse
Cat.No

ABC-TC3241
Product Category

Primary Cells
Size/Quantity

1 vial
Cell Type

Endothelial
Growth Mode

Adherent
Shipping Info

Dry Ice
Growth Conditions

37 ℃, 5% CO2
Source Organ

Retina
Disease

Normal
Biosafety Level

1
Storage

Liquid Nitrogen
Product Type

Mouse Primary Cells
Quality Control

All cells test negative for mycoplasma, bacteria, yeast, and fungi.

Application

  • These endothelial cells are key for modeling the retinal vasculature and its response to disease. C57BL/6 Mouse Retinal Microvascular Endothelial Cells, as a type of mouse endothelial cells within the microvascular system, are used in studies of angiogenesis, blood-retinal barrier function, diabetic retinopathy, and age-related macular degeneration. They also support screening of drugs targeting vascular leakage and neovascularization.

Citation

When you publish your research, please cite our product as “AcceGen Biotech Cat.# XXX-0000”. In return, we’ll give you a $200 coupon. Simply click here and submit your paper’s PubMed ID (PMID).

Frequently Asked Questions

  • What is C57BL/6 Mouse Retinal Microvascular Endothelial Cells?

    C57BL/6 Mouse Retinal Microvascular Endothelial Cells are isolated from retinal microvasculature, characterized by barrier function and angiogenesis, and specifically express VE-cadherin and CD31.

  • Application of C57BL/6 Mouse Retinal Microvascular Endothelial Cells

    C57BL/6 Mouse Retinal Microvascular Endothelial Cells are used in research to study retinal vascular biology, blood-retinal barrier function, and angiogenesis. They are vital for understanding diabetic retinopathy, age-related macular degeneration, and other retinal diseases. These cells enable the evaluation of new therapeutic agents and the exploration of molecular pathways involved in retinal vascular health. Their application in developing treatments for retinal disorders holds significant promise for advancing ocular disease management and therapy.

  • What are the cell culture conditions for C57BL/6 Mouse Retinal Microvascular Endothelial Cells?

    C57BL/6 Mouse Retinal Microvascular Endothelial Cells can be expanded for 3-5 passages at a split ratio of 1:2 under the cell culture conditions specified by AcceGen.

  • What happens to C57BL/6 Mouse Retinal Microvascular Endothelial Cells during in vitro culture?

    C57BL/6 Mouse Retinal Microvascular Endothelial Cells initially adhere to the culture surface as single cells or small clusters, exhibiting a spindle-shaped morphology. As they proliferate, they form a monolayer with a cobblestone appearance, resembling typical endothelial cell morphology. Over time, endothelial cells may display elongated or polygonal shapes depending on their confluence and passage number. Additionally, they may develop tube-like structures when cultured in appropriate angiogenic conditions, mimicking their in vivo behavior.

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