Mouse Valvular Endothelial Cells

Description

Mouse Valvular Endothelial Cells are isolated from mouse heart valve tissue. Valvular endothelial cells line the surface of cardiac valves and play essential roles in maintaining valve homeostasis, regulating inflammatory responses, sensing mechanical forces, and preserving normal valve structure and function. These cells contribute to the regulation of extracellular matrix remodeling and cardiovascular development. Following primary isolation and culture, the cells are cryopreserved for research applications. Mouse valvular endothelial cells have been reported to express endothelial markers including CD31, VE-Cadherin, von Willebrand Factor (vWF), and eNOS. In vitro, the cells display a typical cobblestone-like morphology and grow as an adherent monolayer. These cells are widely used in studies of valvular biology, cardiovascular disease, mechanotransduction, and calcific valve disease. Each lot undergoes rigorous quality control testing to ensure freedom from mycoplasma, fungal, yeast, and bacterial contamination.