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Species | Human |
Cat.No | AM1600 |
Product Category | MicroRNA Agomir/Antagomir |
Size/Quantity | 2 OD, 4 OD, 50 OD (size by request, 1 OD corresponds to 33 ug) |
Shipping Info | Room Temperature |
Storage | -20°C / -80°C |
Product Type | microRNA Agomir/Antagomir |
Label | FAM, CY3, CY5, etc. (optional) |
Component | hsa-miR-224-5p Agomir and/or Antagomir (Product Form: Dry Powder) |
Key Features | *cover all human, mouse, and rat miRNAs listed in miRBase |
MIRacle™ hsa-miR-224-5p miRNA Agomir/Antagomir is a chemically modified synthetic oligonucleotide developed to precisely modulate the activity of endogenous microRNAs. The Agomir functions as a miRNA mimic, effectively enhancing the expression and biological activity of hsa-miR-224-5p. Whereas the Antagomir serves as a sequence-specific antagonist, inhibiting hsa-miR-224-5p function. Both formulations are optimized for high stability and efficacy in in vitro and in vivo settings. AcceGen provides the MIRacle™ series in multiple specifications (2 OD, 4 OD, 50 OD) with HPLC purification to accommodate a diverse range of experimental requirements. These reagents are ideal for investigating the role of hsa-miR-224-5p in key biological processes such as inhibition of osteoblast differentiation, impairment of bone formation, and promotion of tumorigenesis, including its contribution to the progression of thyroid carcinoma. They offer valuable insights into the molecular pathways regulated by hsa-miR-224-5p in skeletal biology and cancer development.
When you publish your research, please cite our product as “AcceGen Biotech Cat.# XXX-0000”. In return, we’ ll give you a $100 coupon. Simply click here and submit your paper’ s PubMed ID (PMID).
MIRacle™ hsa-miR-224-5p Agomir and Antagomir are powerful tools for dissecting the function of miR-224-5p in bone and cancer biology. These reagents enable precise regulation of miR-224-5p, which is known to inhibit osteoblast differentiation, impair bone formation, and promote tumor progression. They’re especially useful for studying miR-224-5p’s role in thyroid carcinoma and other cancers. With strong in vitro and in vivo performance, they support targeted exploration of skeletal remodeling and oncogenic signaling pathways.