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| Product Code | NIH/3T3; NIH3T3; 3T3; 3T3NIH; 3T3-Swiss; Swiss-3T3; Swiss/3T3; Swiss 3T3; Swiss3T3 |
| Species | Mouse |
| Cat.No | ABC-TC0828 |
| Product Category | Tumor Cell Lines |
| Size/Quantity | 1 vial |
| Cell Type | Fibroblast |
| Shipping Info | Dry Ice |
| Growth Conditions | 37 ℃, 5% CO2 |
| Source Organ | Embryo |
| Disease | Normal |
| Biosafety Level | 1 |
| Storage | Liquid Nitrogen |
| Product Type | Mouse Embryo Cell Lines |
NIH-3T3 is a mouse embryonic fibroblast cell line that was originally isolated from NIH/Swiss mouse embryos. NIH-3T3 exhibits fibroblast-like morphology and adherent culture properties. NIH-3T3 is a hypertriploid mouse cell line, and it has tested negative for the ectromelia virus (mousepox). NIH-3T3 displays identifiable clonal abnormalities and is highly susceptible to cellular transformation.
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The NIH-3T3 cell line is a widely used fibroblast model in molecular and cellular biology. Known for its spontaneous immortalization, this mouse embryonic cell line is commonly used in DNA transfection experiments and tumor DNA transfer studies. NIH-3T3 cells enable the identification of transforming oncogenes and support investigations into the molecular mechanisms of cellular transformation and cancer development.
