For research use only
| Cat No. | ABC-TC0828 |
| Product Type | Mouse Embryo Cell Lines |
| Cell Type | Fibroblast |
| Species | Mouse |
| Growth Conditions | 37 ℃, 5% CO2 |
| Source Organ | Embryo |
| Disease | Normal |
| Product Code | NIH/3T3; NIH3T3; 3T3; 3T3NIH; 3T3-Swiss; Swiss-3T3; Swiss/3T3; Swiss 3T3; Swiss3T3 |
NIH-3T3 is a mouse fibroblast cell line, which is widely used in oncogene expression, transformation assays, and tissue remodeling research.
NIH-3T3 (also commonly abbreviated as NIH3T3) is a mouse embryonic fibroblast cell line established from NIH Swiss mouse embryos. These adherent NIH 3T3 fibroblasts display a spindle-shaped, fibroblast-like morphology and are known for their contact inhibition and stable diploid karyotype. NIH-3T3 cells express fibroblast markers such as vimentin and fibronectin, and demonstrate consistent proliferation under standard culture conditions. Their gene expression profile includes regulators of the cell cycle, extracellular matrix, and key signaling pathways related to growth and differentiation. Due to their genetic stability, high transfection efficiency, and ease of maintenance, NIH-3T3 cells are a classic model for studying fibroblast biology, oncogenic transformation, and gene function. They are widely used in focus formation assays and serve as a standard host in evaluating tumorigenic potential of oncogenes and signaling molecules.
| Product Code | NIH/3T3; NIH3T3; 3T3; 3T3NIH; 3T3-Swiss; Swiss-3T3; Swiss/3T3; Swiss 3T3; Swiss3T3 |
| Species | Mouse |
| Cat.No | ABC-TC0828 |
| Product Category | Tumor Cell Lines |
| Size/Quantity | 1 vial |
| Cell Type | Fibroblast |
| Growth Mode | Adherent |
| Shipping Info | Dry Ice |
| Growth Conditions | 37 ℃, 5% CO2 |
| Source Organ | Embryo |
| Disease | Normal |
| Biosafety Level | 1 |
| Storage | Liquid Nitrogen |
| Product Type | Mouse Embryo Cell Lines |
The NIH-3T3 cell line is a widely used fibroblast model in molecular and cellular biology. Known for its spontaneous immortalization, this mouse embryonic cell line is commonly used in DNA transfection experiments and tumor DNA transfer studies. NIH-3T3 cells enable the identification of transforming oncogenes and support investigations into the molecular mechanisms of cellular transformation and cancer development.
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