C57BL/6 Mouse Bone Marrow Mesenchymal Stem Cells

Description

C57BL/6 Mouse Bone Marrow Mesenchymal Stem Cells are primary cells isolated from the bone marrow of healthy C57BL/6 mice. Exhibiting a characteristic spindle-shaped fibroblast-like morphology and adherent culture properties. As multipotent stem cells, they demonstrate robust self-renewal capacity and can differentiate into adipocytes, osteocytes, and chondrocytes under specific induction conditions, serving as essential tools for regenerative medicine and developmental studies. Their distinct surface marker profile: positive for CD29, CD44, and Sca-1, while negative for hematopoietic marker CD117. They are cryopreserved at earliest passage and recommended for use within 3-5 passages to maintain functional integrity.

Application

• C57BL/6 Mouse Bone Marrow Mesenchymal Stem Cells (MSC) offer diverse applications in scientific studies, including adult stem cell differentiation studies, tissue engineering, and cell and gene therapy studies. Benefiting from the mouse model’s suitability for genetic manipulations and cell tracking, these cells are pivotal for assessing MSC behavior as they differentiate into mature phenotypes within the host. Particularly prominent in regenerative medicine and tissue engineering, these cells are instrumental in advancing research in bone, cardiovascular, and nervous system ailments.