For research use only
| Cat No. | ABC-TC3189 |
| Product Type | Mouse Primary Cells |
| Cell Type | Epithelial |
| Species | C57BL/6 Mouse |
| Growth Conditions | 37 ℃, 5% CO2 |
| Source Organ | Esophagus |
| Disease | Normal |
| Storage | Liquid Nitrogen |
C57BL/6 Mouse Esophageal Epithelial Cells ,primary mouse esophageal epithelial cells for gastrointestinal biology and disease modeling research.
The C57BL/6 mouse esophageal epithelial cell line is derived from the esophageal tissue of C57BL/6 mice and represents a robust in vitro model for studying the epithelial barrier of the upper gastrointestinal tract. C57BL/6 mouse esophageal epithelial cells exhibit a cobblestone morphology typical of stratified squamous epithelial cells. They express basal cell cytokeratins such as CK5 and CK14, along with tight junction proteins including claudin-1 and occludin. Additionally, these cells express epithelial markers such as E-cadherin and ZO-1. They retain essential functions including proliferation, differentiation, and barrier formation. This cell line is relevant for studying esophageal pathologies such as gastroesophageal reflux disease (GERD), Barrett’s esophagus, and esophageal carcinoma. It also serves as a model for inflammation and oxidative stress-related studies.
| Species | C57BL/6 Mouse |
| Cat.No | ABC-TC3189 |
| Product Category | Primary Cells |
| Size/Quantity | 1 vial |
| Cell Type | Epithelial |
| Growth Mode | Adherent |
| Shipping Info | Dry Ice |
| Growth Conditions | 37 ℃, 5% CO2 |
| Source Organ | Esophagus |
| Disease | Normal |
| Biosafety Level | 1 |
| Storage | Liquid Nitrogen |
| Product Type | Mouse Primary Cells |
| Quality Control | All cells test negative for mycoplasma, bacteria, yeast, and fungi. |
C57BL/6 mouse esophageal epithelial cells provide a robust model for studying epithelial-stromal interactions and cellular heterogeneity in the esophagus. They enable investigation of mechanisms underlying fibrostenotic diseases like eosinophilic esophagitis fibrosis and advance understanding of epithelial biology. This model supports identification of therapeutic targets for esophageal epithelial disorders.
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