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Immortalized Human Endometrial Stromal Cell Line (HESC)

Product Name

Immortalized Human Endometrial Stromal Cell Line (HESC)

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1 vial

Biosafety Level


Shipping Info

Dry Ice


Liquid Nitrogen


Decidualization of the endometrium, mainly induced by progesterone, is a process of endometrial remodelling where the endometrial stromal cells differentiate into secretory decidual cells in preparation for pregnancy. Decidualized endometrial stromal cells are characterized by release of prolactin (PRL), RI-like growth factor binding protein-1 (IGFBP-1), tissue factor (TF), plasminogen activator inhibitor-1 (PAI-1), and expression of basal lamina components such as laminin, collagen IV, and fibronectin.
Immortalised Human Endometrial Stromal Cells (HESC) are unique in that 1) they display normal karyotype and 2) they respond to hormone stimulation and retain the morphological pattern and biochemical endpoints of decidualization after treatment of oestradiol and medroxyprogesterone, making this cell line a valuable tool in endometrium homeostasis and female reproductive studies.


Non Malignant Myomas

Source Organ


Quality Control

All cells are tested negative for mycoplasma, bacteria, yeast, and fungi.

Recommended Medium And Supplement
Citation Guide

When you publish your research, please cite our product as “AcceGen Biotech Cat.# XXX-0000”. In return, we’ll give you a $100 coupon. Simply click here and submit your paper’s PubMed ID (PMID).


For research use only



Immortalization Method

Serial passaging and transduction with recombinant lentiviruses carrying SV40 Large T antigen.

Growth Conditions

37 ℃, 5% CO2

Cell Type

Stromal Cell

Growth Mode


Product Type

Immortalized Cell Line

Product Image AcceGen Frozen Cells & Cell Lines 1 vial
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