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Human Oligodendrocyte Progenitor Cells

Product Name

Human Oligodendrocyte Progenitor Cells

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Product Code

HOPCs

Cat.No

ABC-TC3732

Species

Human

Size/Quantity

1 vial

Biosafety Level

1

Shipping Info

Dry Ice

Storage

Liquid Nitrogen

Description

Human oligodendrocyte progenitor cells (OPCs) are a population of precursor cells found throughout the central nervous system (CNS). These cells possess the remarkable ability to differentiate into mature oligodendrocytes, which are specialized glial cells responsible for producing myelin, a lipid-rich membrane that provides insulation to neuronal axons. OPCs serve as a pool of migratory and proliferative adult progenitor cells, playing a crucial role in the generation and maintenance of myelinating cells in the CNS. Impaired differentiation of OPCs into mature oligodendrocytes is a significant factor contributing to the development of demyelinating diseases, highlighting the importance of understanding and harnessing the potential of these cells for therapeutic interventions.

 

Why choose Human Oligodendrocyte Progenitor Cells from AcceGen?

Human OPCs are sterile and tested negative for bacteria, fungi, and mycoplasma. They are cryopreserved at a low passage number, ensuring high viability and functionality. Optimal operations and rigorous quality control measures are implemented to maintain their quality and reliability for research and potential therapeutic applications.

Disease

Normal

Source Organ

Brain

Quality Control

All cells test negative for mycoplasma, bacteria, yeast, and fungi.

Recommended Medium And Supplement
Citation Guide

When you publish your research, please cite our product as “AcceGen Biotech Cat.# XXX-0000”. In return, we’ll give you a $100 coupon. Simply click here and submit your paper’s PubMed ID (PMID).

Application

FOR RESEARCH USE ONLY

The applications of Human oligodendrocyte progenitor cells (OPCs) are wide-ranging and hold significant potential for therapeutic interventions. Understanding the molecular mechanisms underlying OPC differentiation is essential for comprehending the processes of myelination and demyelination. Oligodendrocyte pathology is observed in various disorders, including multiple sclerosis, schizophrenia, and Alzheimer’s disease, highlighting the relevance of studying OPCs in these conditions. Transplanting OPCs at the site of injury is being explored as a potential therapeutic strategy for promoting remyelination and facilitating the recovery of locomotor function after spinal cord injury (SCI). Transplantation studies using human OPCs in animal models have shown promising results, offering hope for the development of effective treatments in the future.

Growth Conditions

37 ℃, 5% CO2

Cell Type

Oligodendrocyte

Growth Mode

Adherent

Product Type

Nervous Cells

Product Image AcceGen Frozen Cells & Cell Lines 1 vial
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