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Primary Cells

Human Umbilical Vein Endothelial Cells

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HUVEC are isolated from the vein of the umbilical cord and are commonly used for physiological and pharmacological investigations, such as macromolecule transport, blood coagulation, angiogenesis, and fibrinolysis. Human umbilical vein endothelial cells have played a major role as a model system for the study of the regulation of endothelial cell function and the role […]
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Home | Primary Cells | Human Primary Cells | Blood System Primary Cells | Human Umbilical Vein Endothelial Cells
Product Code

HUVEC
Species

Human
Cat.No

ABC-TC3848
Quality Control

All cells test negative for mycoplasma, bacteria, yeast, and fungi.
Product Category Primary Cells
Size/Quantity

1 vial
Cell Type

Endothelial
Shipping Info

Dry Ice
Growth Conditions

37 ℃, 5% CO2
Source Organ

Umbilical Vein
Disease

Normal
Biosafety Level

1
Storage

Liquid Nitrogen
Product Type

Vascular Cells
Key Features

-Backed by AcceGen advanced technology

-Cryopreserved for highest viability and plating efficiency

-Quality-tested for accurate results

Description

Human Umbilical Vein Endothelial Cells (HUVECs) are isolated from the vein of umbilical cord. These cells exhibit cobblestone morphology with large dark nuclei. They express many important endothelial signal molecules, for example von Willebrand factor (vWF), which is associated with vascular homeostasis regulation, blood platelets mediation and blood vessel wall tone. HUVECs can be identified by the expression of specific marker proteins, including PECAM-1, VE-cadherin, and VWF. These cells maintain many functional properties of vascular endothelium, such as angiogenesis capability, inflammatory response, and vascular permeability regulation. Due to their accessibility and robust growth characteristics, HUVECs have become one of the most widely used in vitro systems for investigating endothelial cell physiology, vascular diseases, and drug screening applications.

AcceGen Frozen Cells & Cell Lines 1 vial
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Citation

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Application

  • Human umbilical vein endothelial cells culture can be used as a laboratory model for studying vasculature and angiogenesis. They are also good cell source to build scaffolds and facilitate vascularisation in tissue engineering. HUVECs can be used to characterize endothelial cell stress response towards physiological and pathophysiological stimuli and build 3D model system to study cell-cell interaction, cell migration, tumour angiogenesis as well as many other researches.

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