Induced Pluripotent Stem Cells (iPSCs)

Stem Cells, also known as progenitor Cells, are self-renewing, pluripotent cells capable of differentiating into various specialized cell types under appropriate conditions. This unique potential makes them essential tools in regenerative medicine, where they are used to restore or replace damaged tissues.

Among the most transformative advancements in stem cell research is the development of induced pluripotent stem cells (iPSCs). iPSCs are pluripotent stem cells generated by reprogramming somatic cells back into a pluripotent state, enabling them to both self-renew indefinitely and differentiate into virtually any cell type in the human body. These cells not only preserve the genetic background of the donor but also bypass the ethical concerns associated with embryonic stem cells, making them an accessible, ethical, and reproducible platform for a wide range of biomedical applications including disease modeling, drug screening, toxicity testing, and personalized medicine. 

The potential of iPSCs lies in their versatility. Through specific directed differentiation protocols, iPSCs can give rise to diverse functional somatic cells -- commonly referred to as iPSC-derived cells, including neurons, cardiomyocytes, hepatocytes, pancreatic β cells, hematopoietic lineages, and more. These cells accurately recapitulate native human tissue physiology and disease phenotypes in vitro, enabling advanced studies in developmental biology, immunology, neurobiology, cardiovascular physiology, and metabolic diseases. iPSC-based models are also instrumental in high-throughput drug screening, toxicity testing, and personalized medicine, allowing researchers to evaluate therapeutic responses in a genetically relevant context.

As the field advances, iPSC technology now extend to complex 3D cultures and organoids that mimic native tissue architecture and function, offering even deeper insight into disease mechanisms.

AcceGen proudly support this growing field with a comprehensive portfolio of high-quality iPSCs and iPSC-derived cells, sourced from various tissue origins and disease states. Our rigorously validated, customizable solutions empower researchers to accelerate discoveries and advance regenerative technologies toward clinical application.