For research use only
| Cat No. | ABC-KC0185 |
| Product Type | CRISPR Knockout Cell Lysate |
| Species | Human |
| Host Cell | HEK293T |
| Storage | Store BCKDHA KO Cell Lysate At -20℃. Please Avoid Repeated Freeze-Thaw Cycles. |
BCKDHA Knockout Cell Lysate supports metabolic pathway studies, enabling analysis of branched-chain amino acid metabolism and disease mechanisms.
The branched-chain alpha-keto acid (BCAA) dehydrogenase (BCKD) complex is an innter mitochondrial enzyme complex that catalyzes the second major step in the catabolism of the branched-chain amino acids leucine, isoleucine, and valine. The BCKD complex consists of three catalytic components: a heterotetrameric (alpha2-beta2) branched-chain alpha-keto acid decarboxylase (E1), a dihydrolipoyl transacylase (E2), and a dihydrolipoamide dehydrogenase (E3). This gene encodes the alpha subunit of the decarboxylase (E1) component. Mutations in this gene result in maple syrup urine disease, type IA. Multiple transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Sep 2009]
| Species | Human |
| Cat.No | ABC-KC0185 |
| Product Category | Transfected Stable Cell Lines |
| Size/Quantity | 100ug |
| Growth Mode | Adherent |
| Shipping Info | Ice Pack |
| Growth Conditions | 37 ℃, 5% CO2 |
| Storage | Store BCKDHA KO Cell Lysate At -20℃. Please Avoid Repeated Freeze-Thaw Cycles. |
| Product Type | CRISPR Knockout Cell Lysate |
| Host Cell | HEK293T |
| Stock | Custom |
When you publish your research, please cite our product as “AcceGen Biotech Cat.# XXX-0000”. In return, we’ll give you a $200 coupon. Simply click here and submit your paper’s PubMed ID (PMID).