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Primary Cells

C57BL/6 Mouse Tracheal and Bronchial Epithelial Cells

  • For research use only

Cat No.

ABC-TC4285
Product Type

Mouse Primary Cells
Cell Type

Epithelial
Species

C57BL/6 Mouse
Growth Conditions

37 ℃, 5% CO2
Source Organ

Tracheal and Bronchial
Disease

Normal
Storage

Liquid Nitrogen

C57BL/6 Mouse Tracheal and Bronchial Epithelial Cells enable airway biology, mucociliary modeling, and infection studies from pathogen-free mice.

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  • C57BL/6 Mouse Tracheal and Bronchial Epithelial Cells
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Home | Primary Cells | Animal Primary Cells | Mouse Primary cells | C57BL/6 Mouse Tracheal and Bronchial Epithelial Cells

Description

C57BL/6 Mouse Primary Tracheal and Bronchial Epithelial Cells are isolated from the tracheal and bronchial tissues of pathogen-free C57BL/6 mice and cryopreserved post-primary culture to maintain native properties. These cells display heterogeneous epithelial morphology, comprising basal (cytokeratin 5⁺), ciliated (FoxJ1⁺), and secretory club cells (secretoglobins), collectively forming a pseudostratified airway epithelium. They retain essential mucociliary clearance and barrier functions critical for respiratory defense. Dysfunction or dysregulation of these cells is implicated in respiratory diseases such as asthma, COPD, pulmonary fibrosis, and viral infections. To preserve viability and function, repeated freeze-thaw cycles should be avoided during culture.

Species

C57BL/6 Mouse
Cat.No

ABC-TC4285
Product Category

Primary Cells
Size/Quantity

1 vial
Cell Type

Epithelial
Growth Mode

Adherent
Shipping Info

Dry Ice
Growth Conditions

37 ℃, 5% CO2
Source Organ

Tracheal and Bronchial
Disease

Normal
Storage

Liquid Nitrogen
Product Type

Mouse Primary Cells
Quality Control

All cells test negative for mycoplasma, bacteria, yeast, and fungi.

Application

  • C57BL/6 mouse primary tracheal and bronchial epithelial cells are widely used for modeling respiratory diseases such as asthma, COPD, and cystic fibrosis, supporting studies on pathophysiology and therapeutic development. They enable investigation of airway barrier integrity, responses to pathogens and environmental insults, and serve as platforms for drug screening and toxicology assessments. These cells are also employed to analyze inflammatory responses, including cytokine release and immune signaling pathways. Additionally, they facilitate studies of mucociliary clearance and hold promise in regenerative medicine through exploration of their differentiation capacity for airway repair.

Citation

When you publish your research, please cite our product as “AcceGen Biotech Cat.# XXX-0000”. In return, we’ll give you a $200 coupon. Simply click here and submit your paper’s PubMed ID (PMID).

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