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Primary Cells

Canine Epididymal Epithelial Cells

  • For research use only

Cat No.

ABC-TC143W
Product Type

Epididymal Cells
Cell Type

Epithelial Cell
Species

Canine
Growth Conditions

37 °C, 5% CO2
Source Organ

Epididymis
Disease

Normal
Storage

Liquid Nitrogen

Canine Epididymal Epithelial Cells are used to study barrier function, mechanotransduction, innate immunity, sperm maturation, and reproductive toxicology.

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  • Canine Epididymal Epithelial Cells
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Home | Primary Cells | Animal Primary Cells | Canine Epididymal Epithelial Cells

Description

Canine Epididymal Epithelial Cells (CEECs) are primary cells isolated from the caput region of the canine epididymis, which retain a polarized pseudostratified morphology. They express tight junction proteins, including claudin‑1 and occludin, which are essential for maintaining the epithelial barrier. These cells are also involved in nutrient transport, as evidenced by the expression of monocarboxylate transporter 1 (MCT1). CEECs play a critical role in mechanotransduction, responding to fluid shear stress by activating primary cilia, which initiate intracellular calcium signaling and cytoskeletal remodeling. Moreover, they exhibit innate immune responses, activating Toll‑like receptor 3 (TLR3) and secreting proinflammatory cytokines, such as tumor necrosis factor‑α (TNF‑α) and monocyte chemoattractant protein‑1 (MCP‑1), upon exposure to viral mimics.

Product Code

Canine Epididymal Epithelial Cells, cEECs, Dog Epididymis Epithelial Cells, Epididymal Epithelium, Canine Epithelial Cells
Species

Canine
Cat.No

ABC-TC143W
Product Category

Primary Cells
Size/Quantity

1 vial
Cell Type

Epithelial Cell
Growth Mode

Adherent
Shipping Info

Dry Ice
Growth Conditions

37 °C, 5% CO2
Source Organ

Epididymis
Disease

Normal
Biosafety Level

1
Storage

Liquid Nitrogen
Product Type

Epididymal Cells
Quality Control

All cells test negative for mycoplasma, bacteria, yeast, and fungi.

Application

  • Canine Epididymal Epithelial Cells (CEECs) are utilized to study epithelial barrier function, specifically nutrient uptake through MCT1-dependent pathways. They are also used in mechanotransduction research to examine primary cilia signaling and cytoskeletal changes under shear stress. CEECs provide an effective model for studying innate immune responses, especially TLR3 activation and subsequent cytokine production. Additionally, these cells support investigations into sperm–epithelial interactions, making them a valuable tool for reproductive and fertility research.

Citation

When you publish your research, please cite our product as “AcceGen Biotech Cat.# XXX-0000”. In return, we’ll give you a $200 coupon. Simply click here and submit your paper’s PubMed ID (PMID).

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