For research use only
| Cat No. | ABC-TC0206 |
| Product Type | Human Melanoma Cell Lines |
| Cell Type | Plasmacytoid |
| Species | Human |
| Growth Conditions | 37 ℃, 5% CO2 |
| Disease | Myeloma |
| Product Code | Delta-47; DELTA-47; Delta 47; DELTA 47; Delta47; DELTA47 |
Human myeloma cell line secreting IgD. Expresses CD4 & CD38.
delta-47 cell line is a myeloma cell line derived from ascites of a 73-year-old male patient. This cell line produces IgD lambda. Omics analyses, including transcriptomic (RNA-seq) profiling and array-based comparative genomic hybridization (CGH), have been conducted on this cell line. The delta-47 cell line expresses CD4 and CD38 and exhibits an aneuploid karyotype characterized by chromosomal abnormalities including 1q+, 2p+, and 14q+. Each lot undergoes rigorous screening and isolation procedures, and is rigorously tested to ensure it is free of contamination from HIV-1, HBV, HCV, Syphilis, Mycoplasma, Fungi, Yeast, and Bacteria.
| Product Code | Delta-47; DELTA-47; Delta 47; DELTA 47; Delta47; DELTA47 |
| Species | Human |
| Cat.No | ABC-TC0206 |
| Product Category | Tumor Cell Lines |
| Size/Quantity | 1 vial |
| Cell Type | Plasmacytoid |
| Shipping Info | Dry Ice |
| Growth Conditions | 37 ℃, 5% CO2 |
| Disease | Myeloma |
| Biosafety Level | 1 |
| Storage | Liquid Nitrogen |
| Product Type | Human Melanoma Cell Lines |
delta-47 serves as a valuable in vitro model for studying multiple myeloma biology, drug resistance, and therapeutic development. Alterations in PDCD4 expression make it valuable for investigating tumor suppressor mechanisms and metastatic pathways, as PDCD4 loss is associated with enhanced invasion and chemoresistance. Researchers utilize delta-47 to explore matrix metalloproteinase (MMP)-mediated metastasis, given its high MMP-2 activity, which facilitates extracellular matrix degradation and tumor dissemination. delta-47 in vitro assays further enable functional studies of cell proliferation, invasion, and drug response, supporting mechanistic research in multiple myeloma.
When you publish your research, please cite our product as “AcceGen Biotech Cat.# XXX-0000”. In return, we’ll give you a $200 coupon. Simply click here and submit your paper’s PubMed ID (PMID).
