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G418 Sulfate (Geneticin)

  • For research use only

Cat No.

ABC-CR003

G418 Sulfate (Geneticin) by AcceGen is an aminoglycoside antibiotic for selecting eukaryotic and prokaryotic cells expressing neomycin resistance.

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  • G418 Sulfate (Geneticin)
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Description

G418 Sulfate (Geneticin®) is an aminoglycoside antibiotic that inhibits protein synthesis by binding to the 80S ribosomal subunit, leading to misreading of mRNA and termination of translation in eukaryotic and prokaryotic cells. It is widely utilized as a selective agent for cells engineered to express the neomycin resistance gene (neo⁺), enabling stable cell line development, CRISPR-Cas9-edited clone selection, and maintenance of genetically modified eukaryotic cells. With broad-spectrum activity against bacteria, yeast, fungi, protozoa, and mammalian cells, G418 is effective in both in vitro and in vivo applications. Its high solubility and stability make it suitable for long-term selection experiments, transgenic model generation, and high-throughput screening in genetic engineering and biomedical research.

Cat.No

ABC-CR003
Product Category

Cell Culture Media, kits & Reagents
Size/Quantity

1 kit
Shipping Info

Room Temperature
Storage

-20°C

Application

  • G418 Sulfate (Geneticin®) is widely used for the selection and maintenance of eukaryotic and prokaryotic cells expressing the neomycin resistance gene (neo⁺). It enables efficient establishment of stable cell lines, CRISPR-Cas9-edited clones, and genetically engineered microbial strains. This antibiotic is critical in selecting transgenic organisms, validating gene function, and conducting high-throughput genetic screens. With high solubility and stability, it supports short- and long-term selection in mammalian, yeast, bacterial, and plant cell cultures. G418 is essential in biomedical research, drug discovery, and the development of recombinant protein production systems.

Citation

When you publish your research, please cite our product as “AcceGen Biotech Cat.# XXX-0000”. In return, we’ll give you a $200 coupon. Simply click here and submit your paper’s PubMed ID (PMID).

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High Viability
To succeed in cell culture
Precision and Reliability
To support a consistent result
Customization Options
Tailed to your research

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