For research use only
| Cat No. | ABC-TC0271 |
| Product Type | Human Sarcoma Cell Lines |
| Species | Human |
| Growth Conditions | 37 ℃, 5% CO2 |
| Disease | Sarcoma |
| Product Code | Giant Cell Tumor |
GCT cell line provides a reliable in vitro model for germ cell tumor research, supporting oncology studies, drug development, and genetic analysis.
GCT (Giant Cell Tumor, TIB-223) is a human cell line isolated from a lung metastasis of a malignant fibrous histiocytoma (MFH) in a 29-year-old male. The cells exhibit adherent monolayer culture properties. It harbors mutations in BRAF, CDKN2A and TP53, and demonstrates expression of colony stimulating activity (CSA), erythroid enhancing activity (EEA), prostaglandin E, and plasminogen activator. GCT is tumorigenic and shows metastatic capacity in the lung. The cells undergo rigorous screening and isolation procedures, and are rigorously tested to ensure they are free of contamination from HIV-1, HBV, HCV, Syphilis, Mycoplasma, Fungi, Yeast, and Bacteria.
| Product Code | Giant Cell Tumor |
| Species | Human |
| Cat.No | ABC-TC0271 |
| Product Category | Tumor Cell Lines |
| Size/Quantity | 1 vial |
| Shipping Info | Dry Ice |
| Growth Conditions | 37 ℃, 5% CO2 |
| Disease | Sarcoma |
| Biosafety Level | 1 |
| Storage | Liquid Nitrogen |
| Product Type | Human Sarcoma Cell Lines |
GCT cells serve as an in vitro model for studying the biology of pleomorphic sarcomas, such as malignant fibrous histiocytoma. Its primary applications include investigating cytokine signaling pathways relevant to hematopoiesis and tumor microenvironment interactions. They are utilized in drug screening, and contribute to cancer genomics research within large-scale projects to identify molecular dependencies in osteolytic tumors.
When you publish your research, please cite our product as “AcceGen Biotech Cat.# XXX-0000”. In return, we’ll give you a $200 coupon. Simply click here and submit your paper’s PubMed ID (PMID).
