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Tumor Cell Lines

H9

  • For research use only

Cat No.

ABC-TC0285

Product Type

Human Lymphocytes Cell Lines

Cell Type

Lymphoblast

Species

Human

Growth Conditions

37 ℃, 5% CO2

H9 cell line provides a pluripotent stem cell model for developmental biology, differentiation studies, and translational research in human cells.

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Description

H9 is a human cutaneous T-cell lymphoma line derived from Sezary syndrome (a leukemic form of mycosis fungoides), it is a derivative of the Hut 78 cell line that was originally isolated from the haematopoietic and/or lymphoid tissue of a 53-year-old white male patient. H9 exhibits lymphoblast-like morphology in suspension culture. H9 consistently expresses CD4 as well as HLA antigens A1, B62, C3, DR4, and DQ3. Karyotypic analysis reveals a near‑triploid chromosomal content, typically about 69 chromosomes (range 58–74). H9 is capable of productive HIV‑1 infection and isolation, making it valuable for virology research. Its tumorigenic nature is confirmed by subcutaneous tumor formation in immunodeficient mice. Its origin from malignant T‑cell lymphoma supports oncogenic phenotype retention and immune antigen expression consistent with cutaneous T‑cell malignancies.

Species

Human

Cat.No

ABC-TC0285

Product Category

Tumor Cell Lines

Size/Quantity

1 vial

Cell Type

Lymphoblast

Shipping Info

Dry Ice

Growth Conditions

37 ℃, 5% CO2

Biosafety Level

1

Storage

Liquid Nitrogen

Product Type

Human Lymphocytes Cell Lines

Application

  • H9 is widely used as a robust in vitro model for HIV‑1 infection and replication studies, particularly for evaluating virus–host interactions, viral entry, and immune modulation in CD4⁺ T‑cells. It enables detailed analysis of alterations in antigen expression and host response following infection and supports investigation of antiviral therapeutics. In addition, H9’s tumorigenic potential allows its use in in vivo xenograft studies for cutaneous T‑cell lymphoma biology and immuno-oncology research.

Citation

When you publish your research, please cite our product as “AcceGen Biotech Cat.# XXX-0000”. In return, we’ll give you a $100 coupon. Simply click here and submit your paper’s PubMed ID (PMID).

Inquiring H9

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High Viability
To succeed in cell culture
Precision and Reliability
To support a consistent result
Customization Options
Tailed to your research

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