HighQC™ Human iPSC-derived Oligodendrocyte-like Cells

Description

HighQC™ Human iPSC-derived Oligodendrocyte-like Cells are carefully characterized cryopreserved cells, derived from skin fibroblasts that are reprogrammed into iPSCs and then differentiated into oligodendrocyte-like cells. These cells provide an ideal experimental model for research on neurodegenerative and demyelinating diseases. The product undergoes strict quality control, including sterility testing, protein expression (ICC), and gene expression (RT-qPCR) analysis. During culture, the cells rapidly mature into oligodendrocyte-like morphology with branched processes and begin expressing oligodendrocyte markers such as MBP, PLP1, CNP, and MAG. The cells undergo stringent quality control and are tested to be negative for HIV-1, HBV, HCV, mycoplasma, bacteria, yeast, and fungi.

Application

• HighQC™ Human iPSC-derived Oligodendrocyte-like Cells are an ideal choice for researchers in a variety of applications, particularly for screening compounds that regulate myelination, phenotypic assays, target validation, neurotoxicity assays, and neuroinflammation assays. When co-cultured with neurons, these cells show significant MBP expression under co-culture conditions, making them an effective tool for studying neurodegenerative diseases, such as multiple sclerosis.