For research use only
| Cat No. | ABC-SC2048 |
| Product Type | Human iPSCs |
| Cell Type | Induced Pluripotent Stem Cell |
| Species | Human |
| Growth Conditions | 37 ℃, 5% CO2 |
| Source Organ | Fibroblast |
| Disease | Dystrophia Myotonica 1 |
| Storage | Liquid Nitrogen |
Cell Type: iPSC; Disease: Dystrophia Myotonica 1; DM1.
HighQC™ Human IPSC From Fibroblast-Dystrophia Myotonica 1 is a disease-specific induced pluripotent stem cell line generated from dermal fibroblasts of a donor diagnosed with Myotonic Dystrophy Type 1 (DM1). The resulting iPSCs (induced pluripotent stem cells) exhibit adherent growth and retain the fundamental capacity for trilineage differentiation into ectoderm, mesoderm, and endoderm derivatives. These iPSCs express the core pluripotency marker SSEA-4. They retain DM1-related cellular features and reflect neuromuscular physiology in vivo. The cells undergo rigorous screening and isolation procedures, and are rigorously tested to ensure they are free of contamination from HIV-1, HBV, HCV, Syphilis, Mycoplasma, Fungi, Yeast, and Bacteria.
| Product Code | HighQC™ Human IPSC From Fibroblast-Dystrophia Myotonica 1, HighQC™ hiPSC DM1, hiPSC-DM1, HighQC™ Human Induced Pluripotent Stem Cells From Fibroblast-Myotonic Dystrophy Type 1 |
| Species | Human |
| Cat.No | ABC-SC2048 |
| Product Category | Stem Cells |
| Size/Quantity | 1 vial |
| Cell Type | Induced Pluripotent Stem Cell |
| Growth Mode | Adherent |
| Shipping Info | Dry Ice |
| Growth Conditions | 37 ℃, 5% CO2 |
| Source Organ | Fibroblast |
| Disease | Dystrophia Myotonica 1 |
| Storage | Liquid Nitrogen |
| Product Type | Human iPSCs |
HighQC™ Human IPSC From Fibroblast-Dystrophia Myotonica 1 serves as a human disease model for developmental and mechanistic studies. Its pluripotent capacity enables differentiation into skeletal muscle cells, cardiomyocytes, and neurons — key lineages affected in myotonic dystrophy type 1 (DM1). This system is used to model multi-systemic pathology, study the toxic effects of expanded Cytosine-Thymine-Guanine (CTG) repeats, and perform drug screening in patient-specific skeletal muscle or cardiac organoids, aiding research into RNA toxicity, muscle development, and cardiac conduction abnormalities.
When you publish your research, please cite our product as "AcceGen Biotech Cat.# XXX-0000". In return, we’ll give you a $200 coupon. Simply click here and submit your paper’s PubMed ID (PMID).