HighQC™ Human IPSC From Fibroblast-Skeletal Displasia

Description

HighQC™ Human IPSC From Fibroblast-Skeletal Displasia is a disease-specific human induced pluripotent stem cell line derived from dermal fibroblasts of a donor diagnosed with a form of Skeletal Dysplasia, a heterogeneous group of genetic disorders affecting bone and cartilage development. The cell line was generated using non-integrating episomal plasmid method. The resulting iPSCs (induced pluripotent stem cells) exhibit adherent growth with a high nucleus-to-cytoplasm ratio and well-defined borders. These human iPSCs maintain pluripotency for skeletal development mechanism research. They retain the fundamental capacity for trilineage differentiation into cell types representing the ectoderm, mesoderm, and endoderm germ layers. Core pluripotency marker SSEA-4 is expressed. The cells undergo rigorous screening and isolation procedures, and are rigorously tested to ensure they are free of contamination from HIV-1, HBV, HCV, Syphilis, Mycoplasma, Fungi, Yeast, and Bacteria.