HighQC™ Human iPSC‑derived Dopaminergic Neurons CHCHD2, R145Q, HOM

Description

HighQC™ Human iPSC‑derived Dopaminergic Neurons CHCHD2, R145Q, HOM are an advanced model for studying Parkinson’s disease (PD) and other neurodegenerative disorders associated with mitochondrial dysfunction. These neurons are derived from human induced pluripotent stem cells (iPSCs) with a homozygous mutation in the CHCHD2 gene, a known genetic variant linked to early-onset Parkinson’s disease and mitochondrial dysfunction. The CHCHD2 protein is essential for mitochondrial function, and mutations in this gene lead to impaired energy production and neuronal death, which is a key feature of Parkinson’s disease pathology.Accegen is proud to provide fully differentiated and functional human iPSC-derived DA neurons that display typical neuronal morphology and express all key markers of DA neurons, e.g., TH, FoxA2. The cells undergo rigorous screening and isolation procedures, and are rigorously tested to ensure they are free of contamination from HIV-1, HBV, HCV, Syphilis, Mycoplasma, Fungi, Yeast, and Bacteria.