For research use only
| Cat No. | ABC-SC226Y |
| Product Type | Induced pluripotent stem cell |
| Species | Human |
| Growth Conditions | 37 ℃, 5% CO2 |
| Source Organ | Fibroblast |
| Disease | Disease |
| Storage | Liquid Nitrogen |
HighQC™ iPSC from Fibroblast-TRISOMY 21 supports Down syndrome research with validated pluripotency, stable trisomy 21 karyotype, and Sendai reprogramming.
HighQC™ iPSC from Fibroblast-TRISOMY 21 is an induced pluripotent stem cell (iPSC) line derived from a donor with Down syndrome (trisomy 21). These cells were reprogrammed from fibroblasts using a Sendai virus vector and belong to the chromosomal abnormalities and genetic diseases collection section. The iPSC from Fibroblast-TRISOMY 21 was cryopreserved and underwent tests for surface antigen expression, alkaline phosphatase activity, and embryoid body (EB) formation, among others, to confirm its pluripotency. These cells express stem cells markers, including SSEA-4 and TRA-1-60. The cells undergo rigorous screening and isolation procedures, and are rigorously tested to ensure they are free of contamination from HIV-1, HBV, HCV, Syphilis, Mycoplasma, Fungi, Yeast, and Bacteria.
| Species | Human |
| Cat.No | ABC-SC226Y |
| Product Category | Stem Cells |
| Size/Quantity | 1 vial |
| Growth Mode | Adherent |
| Shipping Info | Dry Ice |
| Growth Conditions | 37 ℃, 5% CO2 |
| Source Organ | Fibroblast |
| Disease | Disease |
| Biosafety Level | 1 |
| Storage | Liquid Nitrogen |
| Product Type | Induced pluripotent stem cell |
| Quality Control | All cells test negative for mycoplasma, bacteria, yeast, and fungi. |
HighQC™ iPSC from Fibroblast-TRISOMY 21 provides an important resource for the study of Down syndrome (trisomy 21). These cells are widely applied in fields such as disease modeling, developmental biology, drug screening and development. Researchers can use this cell line to investigate the pathogenesis of Down syndrome, its impact on embryonic development, and the biological processes related to cell differentiation. Moreover, HighQC™ iPSC from Fibroblast-TRISOMY 21 can also be used for drug screening, helping to discover potential treatment methods and supporting preclinical drug research. This cell line has broad application prospects in both basic research and translational research.
When you publish your research, please cite our product as “AcceGen Biotech Cat.# XXX-0000”. In return, we’ll give you a $200 coupon. Simply click here and submit your paper’s PubMed ID (PMID).