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Species | Human |
Cat.No | ABC-FC0044 |
Quality Control | All cells test negative for mycoplasma, bacteria, yeast, and fungi. |
Product Category | Stem Cells |
Size/Quantity | 1 vial |
Cell Type | Mesenchymal Stem Cell |
Shipping Info | Dry Ice |
Growth Conditions | 37 ℃, 5% CO2 |
Source Organ | Bone Marrow |
Disease | Normal |
Storage | Liquid Nitrogen |
Product Type | Human Mesenchymal Stem Cells |
HighQC™ RFP-Human Bone Marrow-Derived Mesenchymal Stem Cells (RFP-HBMMSCs) are genetically modified MSCs isolated from healthy human bone marrow. Transfected with RFP-expressing lentiviral vectors and selected via puromycin resistance, they are cryopreserved at passages 3–4, with at least three passages post-thaw. Morphologically fibroblast-like, they adhere to plastic and maintain stable RFP expression confirmed by fluorescence microscopy and flow cytometry. These cells exhibit a normal karyotype and express classic MSC markers (CD73⁺, CD90⁺, CD105⁺) while lacking hematopoietic markers (CD34⁻, CD45⁻). They retain multipotency, differentiating into osteogenic, adipogenic, and chondrogenic lineages, and support hematopoiesis in co-culture systems. Though not pluripotent, they are ideal for lineage tracing, MSC migration, and fluorescent tracking in regenerative studies or tissue engineering.
When you publish your research, please cite our product as "AcceGen Biotech Cat.# XXX-0000". In return, we’ll give you a $100 coupon. Simply click here and submit your paper’s PubMed ID (PMID).
In regenerative medicine, human bone marrow-derived mesenchymal stem cells (HBMMSCs) show promise in tissue repair and regeneration, as they possess the ability to differentiate into various cell types. In the field of gene-based therapeutic interventions, HBMMSCs are engineered to express therapeutic genes and act as vehicles for targeted delivery. They also play a crucial role in studying cell differentiation and gene regulation, shedding light on fundamental cellular processes. Additionally, HBMMSCs are valuable in cell-based screening assays, enabling the evaluation of drug candidates and toxicity testing. With their multifaceted uses, HBMMSCs contribute significantly to advancing our understanding of cellular biology and hold immense potential for therapeutic interventions. RFP-HBMMSCs are effective tools for tracking and imaging MSCs in research and applications.