Human Acute Myeloid Leukemia Bone Marrow Mononuclear Cells (Newly Diagnosed/Untreated)

Description

Human Acute Myeloid Leukemia Bone Marrow Mononuclear Cells are primary mononuclear cells isolated from bone marrow of adult patients with acute myeloid leukemia (AML). This heterogeneous cell population includes leukemic blasts together with lymphocytes and monocytes, exhibiting blast-like morphology and non-adherent growth. These cells reflect AML-associated immune dysregulation and hematopoietic abnormalities, supporting studies of leukemia biology, tumor–immune interactions, and therapeutic response. Commonly expressed markers include CD33, CD117, and HLA-DR, consistent with myeloid lineage characteristics. To ensure the quality of these primary cells, repeated freeze-thaw cycles are not recommended due to the fragile nature of these cells. The cells undergo rigorous screening and isolation procedures, and are rigorously tested to ensure they are free of contamination from HIV-1, HBV, HCV, Syphilis, Mycoplasma, Fungi, Yeast, and Bacteria.