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Human AKT1 (E40K) BAF3 Cell Line

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Home | Transfected Stable Cell Lines | Overexpression Stable Cell Lines | Human AKT1 (E40K) BAF3 Cell Line
Species

Human
Cat.No

ABC-X0063C
Quality Control

All cells test negative for mycoplasma, bacteria, yeast, and fungi.
Product Category Transfected Stable Cell Lines
Size/Quantity

1 vial
Cell Type

Lymphocyte
Shipping Info

Dry Ice
Growth Conditions

37 °C, 5% CO₂
Source Organ

Lymphatic
Disease

Normal
Biosafety Level

1
Storage

Liquid Nitrogen
Product Type

Overexpression Stable Cell Lines
Host Cell

BAF3

Description

Human AKT1 (E40K) BAF3 Cell Line is a genetically engineered model derived from selected murine Ba/F3 parental cell line based on customers’ requirement. The cell line is constructed by integrating human AKT1 gene carrying the E40K mutation into Ba/F3 cells using optimized lentiviral vectors.
Target
AKT1 E40K is an oncogenic mutation located in the PH domain, which promotes constitutive membrane localization and activation of the kinase independent of upstream signals. This variant is associated with enhanced proliferative signaling and tumor development. AcceGen provides precise AKT1-mutant models to facilitate mechanistic studies and targeted therapy development. Polyclonal or monoclonal is optional.

AcceGen Frozen Cells & Cell Lines 1 vial
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Application

  • For research use only

  • The AKT1 (E40K) BAF3 Cell Line is a powerful tool to assess altered AKT signaling, evaluate inhibitors targeting membrane recruitment or kinase activity, and support drug discovery in oncology.

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