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Human Amyotrophic Lateral Sclerosis (ALS) Peripheral Blood Mononuclear Cells

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Amyotrophic lateral sclerosis (ALS) is a specific disease that causes the death of neurons controlling voluntary muscles.&nbsp,Clinical data may include: Medication (current and historical), Disease Severity, MMSE Score.
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Home | Primary Cells | Human Primary Cells | PBMCs | Human Amyotrophic Lateral Sclerosis (ALS) Peripheral Blood Mononuclear Cells
Species

Human
Cat.No

ABC-TC4344
Quality Control

All cells test negative for mycoplasma, bacteria, yeast, and fungi.

Product Category Primary Cells
Size/Quantity

1 vial
Cell Type

Mononuclear Cell
Shipping Info

Dry Ice
Growth Conditions

37 ℃, 5% CO2
Source Organ

Peripheral Blood
Disease

Amyotrophic Lateral Sclerosis
Storage

Liquid Nitrogen
Product Type

Diseased Human Peripheral Blood Mononuclear Cells

Description

Human Amyotrophic Lateral Sclerosis (ALS) Peripheral Blood Mononuclear Cells are a type of mononuclear cell population derived from the peripheral blood of ALS patients, mainly including lymphocytes (T cells, B cells, NK cells) and monocytes. Morphologically, PBMCs are generally round or oval. The core function of PBMCs in ALS patients is to participate in immune regulation and inflammatory response. Their abnormal activation can lead to increased release of proinflammatory cytokines (such as IL-6, TNF-α), reflecting ongoing neuroinflammatory.

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Citation

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Application

  • Human Amyotrophic Lateral Sclerosis (ALS) Peripheral Blood Mononuclear Cells can be used to study the immunopathological mechanism of ALS, biomarker screening and drug efficacy evaluation. In addition, the distinct immune phenotype of PBMCs may offer a potential basis for the early diagnosis of the disease.

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