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Species | Human |
Cat.No | ABC-TC4344 |
Quality Control | All cells test negative for mycoplasma, bacteria, yeast, and fungi. |
Product Category | Primary Cells |
Size/Quantity | 1 vial |
Cell Type | Mononuclear Cell |
Shipping Info | Dry Ice |
Growth Conditions | 37 ℃, 5% CO2 |
Source Organ | Peripheral Blood |
Disease | Amyotrophic Lateral Sclerosis |
Storage | Liquid Nitrogen |
Product Type | Diseased Human Peripheral Blood Mononuclear Cells |
Human Amyotrophic Lateral Sclerosis (ALS) Peripheral Blood Mononuclear Cells are a type of mononuclear cell population derived from the peripheral blood of ALS patients, mainly including lymphocytes (T cells, B cells, NK cells) and monocytes. Morphologically, PBMCs are generally round or oval. The core function of PBMCs in ALS patients is to participate in immune regulation and inflammatory response. Their abnormal activation can lead to increased release of proinflammatory cytokines (such as IL-6, TNF-α), reflecting ongoing neuroinflammatory.
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Human Amyotrophic Lateral Sclerosis (ALS) Peripheral Blood Mononuclear Cells can be used to study the immunopathological mechanism of ALS, biomarker screening and drug efficacy evaluation. In addition, the distinct immune phenotype of PBMCs may offer a potential basis for the early diagnosis of the disease.