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Human Artherosclerosis Peripheral Blood Mononuclear Cells

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Atherosclerosis is a condition where the arteries become narrowed and hardened due to a buildup of plaque around the artery wall. It is also known as arteriosclerotic vascular disease.
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Home | Primary Cells | Human Primary Cells | PBMCs | Human Artherosclerosis Peripheral Blood Mononuclear Cells
Species

Human
Cat.No

ABC-TC4346
Quality Control

All cells test negative for mycoplasma, bacteria, yeast, and fungi.

Product Category Primary Cells
Size/Quantity

1 vial
Cell Type

Mononuclear Cell
Shipping Info

Dry Ice
Growth Conditions

37 ℃, 5% CO2
Source Organ

Peripheral Blood
Disease

Artherosclerosis
Storage

Liquid Nitrogen
Product Type

Diseased Human Peripheral Blood Mononuclear Cells

Description

Human Artherosclerosis Peripheral Blood Mononuclear Cells are a group of immune cells isolated from the peripheral blood of patients with atherosclerosis, mainly including lymphocytes (T cells, B cells, NK cells) and monocytes. Morphologically, thses cells are round or oval in shape. These cells play a core role in the immune inflammatory response of atherosclerosis: monocytes can differentiate into macrophages, and T cells aggravate vascular wall inflammation by secreting proinflammatory factors such as IFN-γ and TNF-α, while regulatory T cells (Treg) have anti-inflammatory protective effects.

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Citation

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Application

  • Human Artherosclerosis Peripheral Blood Mononuclear Cells can be used as an in vitro cell model to study the immune mechanism of atherosclerosis. These cells can also be used for drug screening and efficacy testing, such as testing the effects of anti-inflammatory drugs, immunomodulators or lipid-lowering drugs on immune cell function.

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