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Human AXL (G626R) BAF3 Cell Line

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Home | Transfected Stable Cell Lines | Overexpression Stable Cell Lines | Human AXL (G626R) BAF3 Cell Line
Species

Human
Cat.No

ABC-X0405C
Quality Control

All cells test negative for mycoplasma, bacteria, yeast, and fungi.
Product Category Transfected Stable Cell Lines
Size/Quantity

1 vial
Cell Type

Lymphocytes
Shipping Info

Dry Ice
Growth Conditions

37 °C, 5% CO2
Source Organ

Lymphatic
Disease

Normal
Biosafety Level

1
Storage

Liquid Nitrogen
Product Type

Overexpression Stable Cell Lines
Host Cell

BAF3

Description

Human AXL (G626R) BAF3 Cell Line is a stable Ba/F3 cell line expressing the G626R-mutant human AXL gene. This mutation renders the Ba/F3 cells IL-3–independent, supporting their use in modeling oncogenic AXL signaling.
Target
AXL is a member of the TAM receptor tyrosine kinase family and regulates proliferation, survival, and immune evasion. The G626R mutation enhances AXL kinase activity and has been implicated in resistance to targeted therapies.
AcceGen offers generation of stable overexpression cell lines targeting any gene of your interest. Polyclonal or monoclonal is optional based on customers’ research needs.

AcceGen Frozen Cells & Cell Lines 1 vial
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Application

  • For research use only

  • Ideal for characterizing AXL-driven signaling and assessing the efficacy of anti-AXL therapeutic strategies.

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