Transfected Stable Cell Lines

Human B7H3_IgV2 CHOK1 Cell Line

  • For research use only

Cat No.

ABC-X0102C

Product Type

Overexpression Stable Cell Lines

Cell Type

Epithelial

Species

Human

Host Cell

CHOK1

Source Organ

Ovary

Disease

Normal

Storage

Liquid Nitrogen

The B7H3-IgV2 CHOK1 Cell Line supports research on immune checkpoint modulation and enables drug screening for tumor immune evasion mechanisms.

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Description

Human B7H3_IgV2 CHOK1 Cell Line is a genetically modified CHOK1 model overexpressing the immunoglobulin V2 domain of human B7-H3 via lentiviral vector integration. Transgene expression is confirmed by qRT-PCR, and cells are cultured under low-passage conditions (<P20). Target B7-H3 (CD276) is an immune checkpoint molecule involved in tumor immune evasion and is overexpressed in various malignancies. The IgV2 domain plays a key role in receptor binding and signal transduction. AcceGen offers generation of stable overexpression cell lines targeting any gene of your interest. Polyclonal or monoclonal is optional based on customers' research needs.

Species

Human

Cat.No

ABC-X0102C

Product Category

Transfected Stable Cell Lines

Size/Quantity

1 vial

Cell Type

Epithelial

Growth Mode

Adherent

Shipping Info

Dry Ice

Growth Conditions

37 °C, 5% CO2

Source Organ

Ovary

Disease

Normal

Biosafety Level

1

Storage

Liquid Nitrogen

Product Type

Overexpression Stable Cell Lines

Host Cell

CHOK1

Quality Control

All cells test negative for mycoplasma, bacteria, yeast, and fungi.

Application

  • This cell model is ideal for evaluating B7-H3-targeted immunotherapies, including monoclonal antibodies and CAR-T constructs, and for studying immune checkpoint pathways in tumor settings.

Inquiring Human B7H3_IgV2 CHOK1 Cell Line

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High Viability
To succeed in cell culture
Precision and Reliability
To support a consistent result
Customization Options
Tailed to your research

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