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Transfected Stable Cell Lines

Human B7H3_IgV2 CHOK1 Cell Line

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Home | Transfected Stable Cell Lines | Overexpression Stable Cell Lines | Human B7H3_IgV2 CHOK1 Cell Line
Species

Human
Cat.No

ABC-X0102C
Quality Control

All cells test negative for mycoplasma, bacteria, yeast, and fungi.
Product Category Transfected Stable Cell Lines
Size/Quantity

1 vial
Cell Type

Epithelial
Shipping Info

Dry Ice
Growth Conditions

37 °C, 5% CO2
Source Organ

Ovary
Disease

Normal
Biosafety Level

1
Storage

Liquid Nitrogen
Product Type

Overexpression Stable Cell Lines
Host Cell

CHOK1

Description

Human B7H3_IgV2 CHOK1 Cell Line is a genetically modified CHOK1 model overexpressing the immunoglobulin V2 domain of human B7-H3 via lentiviral vector integration. Transgene expression is confirmed by qRT-PCR, and cells are cultured under low-passage conditions (<P20). Target B7-H3 (CD276) is an immune checkpoint molecule involved in tumor immune evasion and is overexpressed in various malignancies. The IgV2 domain plays a key role in receptor binding and signal transduction. AcceGen offers generation of stable overexpression cell lines targeting any gene of your interest. Polyclonal or monoclonal is optional based on customers' research needs.

AcceGen Frozen Cells & Cell Lines 1 vial
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Application

  • For research use only

  • This cell model is ideal for evaluating B7-H3-targeted immunotherapies, including monoclonal antibodies and CAR-T constructs, and for studying immune checkpoint pathways in tumor settings.

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