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Transfected Stable Cell Lines

Human BCR_ABL (A337T) BAF3 Cell Line

  • For research use only

Cat No.

ABC-X0333C
Product Type

Overexpression Stable Cell Lines
Cell Type

Lymphocytes
Species

Human
Host Cell

BAF3
Source Organ

Lymphatic
Disease

Normal
Storage

Liquid Nitrogen

Human BCR_ABL (A337T) BAF3 Cell Line is designed to evaluate the functional consequences of BCR-ABL variants on kinase activity and drug response.

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  • Human BCR_ABL (A337T) BAF3 Cell Line
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Home | Transfected Stable Cell Lines | Overexpression Stable Cell Lines | Human BCR_ABL (A337T) BAF3 Cell Line

Description

Human BCR_ABL (A337T) BAF3 Overexpression Cell Line is constructed via lentiviral integration of human BCR-ABL carrying the A337T mutation into Ba/F3 cells. The cells are confirmed at the transcript level and maintained below passage 20.
Target
A337T is a clinically relevant BCR-ABL mutation linked to reduced sensitivity to tyrosine kinase inhibitors. It affects protein conformation and contributes to drug-resistant leukemic phenotypes. AcceGen offers generation of stable overexpression cell lines targeting any gene of your interest. Polyclonal or monoclonal is optional based on customers’ research needs.

Species

Human
Cat.No

ABC-X0333C
Product Category

Transfected Stable Cell Lines
Size/Quantity

1 vial
Cell Type

Lymphocytes
Growth Mode

Suspension
Shipping Info

Dry Ice
Growth Conditions

37 °C, 5% CO2
Source Organ

Lymphatic
Disease

Normal
Biosafety Level

1
Storage

Liquid Nitrogen
Product Type

Overexpression Stable Cell Lines
Host Cell

BAF3
Quality Control

All cells test negative for mycoplasma, bacteria, yeast, and fungi.

Application

  • This cell model facilitates detailed investigation of A337T-associated resistance mechanisms and enables preclinical screening of next-gen BCR-ABL inhibitors.

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High Viability
To succeed in cell culture
Precision and Reliability
To support a consistent result
Customization Options
Tailed to your research

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