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Transfected Stable Cell Lines

Human BCR_ABL (M244V) BAF3 Cell Line

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Home | Transfected Stable Cell Lines | Overexpression Stable Cell Lines | Human BCR_ABL (M244V) BAF3 Cell Line
Species

Human
Cat.No

ABC-X0425C
Quality Control

All cells test negative for mycoplasma, bacteria, yeast, and fungi.
Product Category Transfected Stable Cell Lines
Size/Quantity

1 vial
Cell Type

Lymphocytes
Shipping Info

Dry Ice
Growth Conditions

37 °C, 5% CO2
Source Organ

Lymphatic
Disease

Normal
Biosafety Level

1
Storage

Liquid Nitrogen
Product Type

Overexpression Stable Cell Lines
Host Cell

BAF3

Description

Human BCR_ABL (M244V) BAF3 Cell Line is a Ba/F3 cell line engineered to express the M244V-mutant version of the BCR_ABL fusion gene, enabling cytokine-independent growth.
Target
The BCR_ABL fusion gene, characteristic of chronic myeloid leukemia, encodes a constitutively active tyrosine kinase. The M244V mutation is linked to resistance against ABL kinase inhibitors. AcceGen offers generation of stable overexpression cell lines targeting any gene of your interest. Polyclonal or monoclonal is optional based on customers’ research needs.

AcceGen Frozen Cells & Cell Lines 1 vial
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Application

  • For research use only

  • Ideal for investigating resistance mechanisms to BCR_ABL inhibitors and for validating novel therapeutics.

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To support a consistent result
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