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Human Brain Vascular Pericytes

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Pericytes are contractile smooth muscle-like cells that cover the abluminal surface of microvessels. They are most abundant on venules and are common on capillaries. The pericytes population is highly variable between different tissues and organs and appears to show functional heterogeneity. Three major functional roles have been ascribed to pericytes associated with central nervous system […]
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Home | Primary Cells | Human Primary Cells | Nervous System Primary Cells | Human Brain Vascular Pericytes
Product Code

HBVP
Species

Human
Cat.No

ABC-TC3526
Quality Control

All cells test negative for mycoplasma, bacteria, yeast, and fungi.
Product Category Primary Cells
Size/Quantity

1 vial
Cell Type

Pericyte
Shipping Info

Dry Ice
Growth Conditions

37 ℃, 5% CO2
Source Organ

Brain
Disease

Normal
Biosafety Level

1
Storage

Liquid Nitrogen
Product Type

Nervous Cells

Description

Human Brain Vascular Pericytes, derived from normal human brain cortical tissue, are contractile smooth muscle-like cells that envelop the abluminal surface of microvessels, Human Brain Vascular Pericyteswith a higher prevalence on venules and a presence on capillaries. This pericyte population exhibits notable variability across tissues and organs, displaying functional diversity. In the context of the brain, they serve as pivotal contributors to the establishment and maintenance of the blood-brain barrier, control angiogenesis, support endothelial cell survival, and engage in the clearance and phagocytosis of cellular debris, collectively safeguarding brain vascular integrity and function.

 

Why choose Human Brain Vascular Pericytes from AcceGen?

Human Brain Vascular Pericytes, cryopreserved at passage one (P1), are supplied in each vial with over 5×105 viable cells, ensuring ample material for experimentation. These cells come with a guarantee of expanding for up to 15 population doublings when following AcceGen’s provided instructions, facilitating robust and extended research opportunities.

AcceGen Frozen Cells & Cell Lines 1 vial
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Citation

When you publish your research, please cite our product as “AcceGen Biotech Cat.# XXX-0000”. In return, we’ll give you a $100 coupon. Simply click here and submit your paper’s PubMed ID (PMID).

Application

  • FOR RESEARCH USE ONLY

  • Human Brain Vascular Pericytes find pivotal applications in various pathological conditions owing to their close association with endothelial cell structure and blood flow regulation. Both excess and deficiency in vascular pericyte activity have been linked to disorders such as hypertension, diabetic retinopathy, Alzheimer’s disease, multiple sclerosis, and the formation of central nervous system tumors. These pericytes serve as valuable tools for research aimed at understanding and potentially mitigating these complex diseases, shedding light on potential therapeutic interventions and diagnostic strategies.

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