Transfected Stable Cell Lines

Human CCDC6_RET BAF3 Cell Line

  • For research use only

Cat No.

ABC-X0193C

Product Type

Overexpression Stable Cell Lines

Cell Type

Lymphocytes

Species

Human

Host Cell

BAF3

Source Organ

Lymphatic

Disease

Normal

Storage

Liquid Nitrogen

The human CCDC6-RET BAF3 Cell Line supports RET fusion research, aiding in the study of oncogenic signaling and screening of RET pathway inhibitors.

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Description

Human CCDC6_RET BAF3 Cell Line is a murine pro-B cell model stably expressing the CCDC6-RET fusion oncogene via lentiviral vector delivery. Expression is validated by qRT-PCR, and cultures are maintained at low passage (<P20). Target CCDC6-RET is a recurrent fusion in papillary thyroid carcinoma and lung adenocarcinoma. It drives RAS-MAPK pathway activation and cellular transformation. AcceGen offers generation of stable overexpression cell lines targeting any gene of your interest. Polyclonal or monoclonal is optional based on customers' research needs.

Species

Human

Cat.No

ABC-X0193C

Product Category

Transfected Stable Cell Lines

Size/Quantity

1 vial

Cell Type

Lymphocytes

Growth Mode

Suspension

Shipping Info

Dry Ice

Growth Conditions

37 °C, 5% CO2

Source Organ

Lymphatic

Disease

Normal

Biosafety Level

1

Storage

Liquid Nitrogen

Product Type

Overexpression Stable Cell Lines

Host Cell

BAF3

Quality Control

All cells test negative for mycoplasma, bacteria, yeast, and fungi.

Application

  • This model supports RET fusion-targeted drug testing, mechanistic studies, and resistance mechanism characterization in oncogenic RET-driven cancers.

Inquiring Human CCDC6_RET BAF3 Cell Line

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High Viability
To succeed in cell culture
Precision and Reliability
To support a consistent result
Customization Options
Tailed to your research

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