Description
Human Chronic Lymphoid Leukemia PB CD19+/CD5+ B Cells are primary lymphocytes isolated from the peripheral blood of newly diagnosed, untreated chronic lymphocytic leukemia (CLL) patients. Following isolation, the cells are cryopreserved to maintain their native phenotype. Morphologically, CLL B cells display a small, mature lymphoid appearance with scant cytoplasm and a round nucleus. These cells are non-adherent, non-proliferative under standard in vitro conditions, and are not suitable for passaging. Cytogenetic abnormalities such as del(13q), trisomy 12, or del(11q) are frequently observed in this CLL subtype. Functionally, CD19+/CD5+ B cells play a critical role in the pathology of CLL, particularly through dysregulated B-cell receptor (BCR) signaling, impaired apoptosis, and immune evasion. Each lot undergoes rigorous screening and isolation procedures, and is rigorously tested to ensure it is free of contamination from HIV-1, HBV, HCV, Syphilis, Mycoplasma, Fungi, Yeast, and Bacteria.
| Product Code |
Human Chronic Lymphoid Leukemia PB CD19+/CD5+ B Cells (Newly Diagnosed/Untreated), Human CLL PB CD19+/CD5+ B Cells, CD19+/CD5+ B Cells, CLL B Cells, CD19+/CD5+ B Cells, CLL PB CD19+/CD5+ (ND)
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| Species |
Human
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| Cat.No |
ABC-TC3346
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| Product Category |
Primary Cells |
| Size/Quantity |
1 vial
|
| Cell Type |
B Cell
|
| Growth Mode |
Suspension
|
| Shipping Info |
Dry Ice
|
| Growth Conditions |
37 ℃, 5% CO2
|
| Source Organ |
Peripheral Blood
|
| Disease |
Chronic Lymphoid Leukemia
|
| Biosafety Level |
1
|
| Storage |
Liquid Nitrogen
|
| Product Type |
Immune Cells
|
| Quality Control |
All cells test negative for mycoplasma, bacteria, yeast, and fungi.
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