+1 862-686-2696
Featured Products
Primary Cells
Immortalized Cell Lines
Stem Cells
Tumor Cell Lines
Transfected Stable Cell Lines
Exosomes
MicroRNA Agomir/Antagomir
Nucleic Acid Kits
Explore Products
Cell
Cell
MicroRNA
MicroRNA
Test and Analysis
Test and Analysis
Transfected Stable Cell Lines

Human cKIT (V559D_Y823D) BAF3 Cell Line

  • BSL

    1

  • 61
Request Your Custom Quote Today

Discover top-quality products tailored for scientific and medical research. Request a personalized quote today
to enhance your projects.

Get a Quote
  • High Purity Levels
  • Precision and Reliability
  • Customization Options
Home | Transfected Stable Cell Lines | Overexpression Stable Cell Lines | Human cKIT (V559D_Y823D) BAF3 Cell Line
Species

Human
Cat.No

ABC-X0380C
Quality Control

All cells test negative for mycoplasma, bacteria, yeast, and fungi.
Product Category Transfected Stable Cell Lines
Size/Quantity

1 vial
Cell Type

Lymphocytes
Shipping Info

Dry Ice
Growth Conditions

37 °C, 5% CO2
Source Organ

Lymphatic
Disease

Normal
Biosafety Level

1
Storage

Liquid Nitrogen
Product Type

Overexpression Stable Cell Lines
Host Cell

BAF3

Description

Human cKIT (V559D_Y823D) BAF3 Cell Line is a genetically engineered model derived from selected murine pro-B Ba/F3 parental cell line based on customers’ requirement. cKIT (V559D_Y823D) BAF3 overexpression cell line is generated by stable integration of an exogenous human cKIT gene harboring V559D and Y823D mutations into BAF3 host cells using our optimized transduction of lentiviral vectors. Overexpression clone is validated at gene level by qRT-PCR.
Target
Mutations in cKIT, a receptor tyrosine kinase, drive constitutive activation of downstream MAPK and PI3K pathways. The V559D and Y823D mutations synergistically promote oncogenic signaling and may influence response to tyrosine kinase inhibitors. AcceGen offers generation of stable overexpression cell lines targeting any gene of your interest. Polyclonal or monoclonal is optional based on customers’ research needs.

AcceGen Frozen Cells & Cell Lines 1 vial
View Product Image

Application

  • For research use only

  • The cKIT (V559D_Y823D) BAF3 Overexpression Cell Line is a valuable platform for elucidating mutation-specific cKIT signaling and assessing targeted therapeutic responses in hematologic malignancies.

  • Online Inquiry
  • Product Reviews

Inquiring Human cKIT (V559D_Y823D) BAF3 Cell Line

We know how valuable your research is to you, but are you wondering what you can expect to pay for quick accurate results every time? Fill out a request in the form below and we’ll get back to you within 24 hours with a quote.
High Viability
To succeed in cell culture
Precision and Reliability
To support a consistent result
Customization Options
Tailed to your research

Tags

Let's Advance Life Science Research Together

Contact Us
AcceGen Scroll Top Button