For research use only
| Cat No. | ABC-X0292C |
| Product Type | Overexpression Stable Cell Lines |
| Cell Type | Lymphocytes |
| Species | Human |
| Host Cell | BAF3 |
| Source Organ | Lymphatic |
| Disease | Normal |
| Storage | Liquid Nitrogen |
Human CLIP1_LTK (I565N) BAF3 Cell Line is designed to study the role of CLIP1_LTK mutations in cancer cell signaling and treatment resistance.
Human CLIP1_LTK (I565N) BAF3 Cell Line is a genetically modified Ba/F3 model expressing the I565N mutant variant of the CLIP1-LTK fusion gene. Stable transduction was performed using lentiviral vectors, and cells are validated by qRT-PCR at low passage.
Target
I565N mutation alters the regulatory region of LTK, increasing kinase signaling. It is involved in tumorigenic processes across hematological cancers. AcceGen offers generation of stable overexpression cell lines targeting any gene of your interest. Polyclonal or monoclonal is optional based on customers’ research needs.
| Species | Human |
| Cat.No | ABC-X0292C |
| Product Category | Transfected Stable Cell Lines |
| Size/Quantity | 1 vial |
| Cell Type | Lymphocytes |
| Growth Mode | Suspension |
| Shipping Info | Dry Ice |
| Growth Conditions | 37 °C, 5% CO2 |
| Source Organ | Lymphatic |
| Disease | Normal |
| Biosafety Level | 1 |
| Storage | Liquid Nitrogen |
| Product Type | Overexpression Stable Cell Lines |
| Host Cell | BAF3 |
| Quality Control | All cells test negative for mycoplasma, bacteria, yeast, and fungi. |
Ideal for studying functional implications of I565N mutation and identifying effective LTK inhibitors or combinatorial drug strategies.