Explore Products
Primary Cells

Human Crohn’ s Disease Peripheral Blood Mononuclear Cells

  • BSL

    1

  • 176
Peripheral blood mononuclear cells are isolated from Crohn’s Disease peripheral blood by diluting the whole blood with PBS and using gradient separation techniques. After centrifugation,the mononuclear cell layer is collected. Mononuclear Cells can be processed further to isolate subpopulations. Fresh Crohn’s PBMCs is available upon request.
Request Your Custom Quote Today

Discover top-quality products tailored for scientific and medical research. Request a personalized quote today
to enhance your projects.

Get a Quote
  • High Purity Levels
  • Precision and Reliability
  • Customization Options
Species

Human

Cat.No

ABC-TC3391

Quality Control

All cells test negative for mycoplasma, bacteria, yeast, and fungi.

Product Category Primary Cells
Size/Quantity

1 vial

Cell Type

Mononuclear Cell

Shipping Info

Dry Ice

Growth Conditions

37 ℃, 5% CO2

Source Organ

Peripheral Blood

Disease

Crohn’ s Disease

Biosafety Level

1

Storage

Liquid Nitrogen

Product Type

Diseased Human Peripheral Blood Mononuclear Cells

Description

Human Crohn’s Disease Peripheral Blood Mononuclear Cells are derived from the peripheral blood of patients with Crohn’s Disease (CD). PBMCs, including lymphocytes (T cells, B cells, NK cells) and monocytes.Lymphocytes (T cells, B cells, NK cells) and monocytes are enriched from whole blood by density gradient centrifugation (such as Ficoll separation medium). Abnormally activated immune cell subsets may exist in PBMCs of patients with Crohn’s disease, such as changes in the proportion of CD4+ memory T cells or upregulated expression of monocyte chemokine receptors. Some subsets may exhibit upregulation of chemokine receptors (e.g., CCR2 on monocytes), activation markers (e.g., CD69, HLA-DR on T cells), or transcription factors (e.g., RORγt in Th17 cells), assessed by flow cytometry or qPCR.These cells are involved in abnormal immune responses, including overactivation of Th1/Th17 cells, defective regulatory T cell (Treg) function, and abnormal differentiation of monocytes into macrophages, leading to intestinal mucosal barrier destruction and chronic inflammation.

View Product Image

Citation

When you publish your research, please cite our product as "AcceGen Biotech Cat.# XXX-0000". In return, we’ll give you a $100 coupon. Simply click here and submit your paper’s PubMed ID (PMID).

Application

  • Human Crohn’s Disease Peripheral Blood Mononuclear Cells can be used to study the immune-driven mechanism of intestinal mucosal barrier destruction and chronic inflammation, and provide a theoretical basis for disease classification and targeted intervention. These cells can also be used for high-throughput drug screening and efficacy evaluation.

Inquiring Human Crohn’ s Disease Peripheral Blood Mononuclear Cells

We know how valuable your research is to you, but are you wondering what you can expect to pay for quick accurate results every time? Fill out a request in the form below and we’ll get back to you within 24 hours with a quote.
High Viability
To succeed in cell culture
Precision and Reliability
To support a consistent result
Customization Options
Tailed to your research

Tags

AcceGen Scroll Top Button