Primary Cells

Human Dermal Microvascular Endothelial Cells, Neonatal

  • For research use only

Cat No.

ABC-TC3403

Product Type

Dermal Cells

Cell Type

Endothelial

Species

Human

Growth Conditions

37 ℃, 5% CO2

Source Organ

Dermal

Disease

Normal

Storage

Liquid Nitrogen

Human Dermal Microvascular Endothelial Cells provide primary vascular cells for modeling angiogenesis and translational vascular biology studies.

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Description

Human Dermal Microvascular Endothelial Cells (HDMECs), Neonatal are isolated from the dermal microvasculature of neonatal human skin tissue, obtained from skin tissue. The source tissue is the dermal layer of neonatal skin, and the isolated cells are primary microvascular endothelial cells characterized by their cobblestone morphology and adherent growth pattern in culture. These cells play a critical role in forming capillaries and small blood vessels during early development. HDMECs express classical endothelial markers including CD31, von Willebrand factor (vWF), or VE-cadherin, confirmed by flow cytometry and immunocytochemistry. Karyotype analysis demonstrates chromosomal stability, and cells are cryopreserved at early passage to maintain their proliferative capacity and phenotypic integrity. Each lot undergoes rigorous screening and isolation procedures and is tested to ensure it is free from contamination by HIV-1, HBV, HCV, Syphilis, Mycoplasma, Fungi, Yeast, and Bacteria.
Product Code

Human Dermal Microvascular Endothelial Cells, Neonatal, Human Dermal Microvascular Endothelial Cells, Microvascular Endothelial Cells, ECs, DMVECs, Neonatal DMVECs

Species

Human

Cat.No

ABC-TC3403

Product Category

Primary Cells

Size/Quantity

1 vial

Cell Type

Endothelial

Growth Mode

Adherent

Shipping Info

Dry Ice

Growth Conditions

37 ℃, 5% CO2

Source Organ

Dermal

Disease

Normal

Biosafety Level

1

Storage

Liquid Nitrogen

Product Type

Dermal Cells

Quality Control

All cells test negative for mycoplasma, bacteria, yeast, and fungi.

Application

  • Human Dermal Microvascular Endothelial Cells (HDMECs), Neonatal are widely utilized in angiogenesis research, vascular biology, wound healing studies, and tissue engineering. Their robust proliferation and angiogenic potential make them ideal for modeling developmental vascular processes, drug screening, and constructing vascularized tissue models. Additionally, they can be employed to investigate the impact of environmental factors and genetic variations on early-stage vascular development and function, offering insights into the origins of vascular-related diseases.

Citation

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