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Primary Cells

Human Diffuse Large B-Cell Lymphoma Bone Marrow Mononuclear Cells (Newly Diagnosed/Untreated)

  • For research use only

Cat No.

ABC-TC3404
Product Type

Immune Cells
Cell Type

Mononuclear Cell
Species

Human
Growth Conditions

37 ℃, 5% CO2
Source Organ

Bone Marrow
Disease

Diffuse Large B-Cell Lymphoma
Storage

Liquid Nitrogen

Human Diffuse Large B-Cell Lymphoma Bone Marrow Mononuclear Cells (Newly Diagnosed/Untreated) for immune profiling and lymphoma progression research.

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  • Human Diffuse Large B-Cell Lymphoma Bone Marrow Mononuclear Cells (Newly Diagnosed/Untreated)
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Home | Primary Cells | Human Primary Cells | Immune System Primary Cells | Human Diffuse Large B-Cell Lymphoma Bone Marrow Mononuclear Cells (Newly Diagnosed/Untreated)

Description

Human Diffuse Large B-Cell Lymphoma (DLBCL) Bone Marrow Mononuclear Cells (Newly Diagnosed/Untreated) are isolated from bone marrow aspirates of newly diagnosed, untreated human patients with confirmed DLBCL. The isolated cells are mononuclear cells comprising malignant B lymphocytes along with supporting stromal and immune cells. These cells exhibit a heterogeneous population including large, atypical B cells characteristic of DLBCL morphology. These cells grow in suspension culture, are non-adherent, and display limited proliferative capacity ex vivo. Flow cytometry analysis shows high expression of CD19, CD20, CD22, and other B-cell markers, with clonal rearrangements confirmed by molecular assays. Karyotyping reveals chromosomal abnormalities typical of DLBCL. Each lot undergoes rigorous screening and isolation procedures and is tested to ensure it is free from contamination by HIV-1, HBV, HCV, Syphilis, Mycoplasma, Fungi, Yeast, and Bacteria.
Product Code

Human Diffuse Large B-Cell Lymphoma Bone Marrow Mononuclear Cells (Newly Diagnosed/Untreated), Human DLBCL Bone Marrow Mononuclear Cells, Bone Marrow Mononuclear Cells, BMMCs, MNCs, DLBCL BM MNCs (ND)
Species

Human
Cat.No

ABC-TC3404
Product Category

Primary Cells
Size/Quantity

1 vial
Cell Type

Mononuclear Cell
Growth Mode

Adherent
Shipping Info

Dry Ice
Growth Conditions

37 ℃, 5% CO2
Source Organ

Bone Marrow
Disease

Diffuse Large B-Cell Lymphoma
Biosafety Level

1
Storage

Liquid Nitrogen
Product Type

Immune Cells
Quality Control

All cells test negative for mycoplasma, bacteria, yeast, and fungi.

Application

  • Human Diffuse Large B-Cell Lymphoma (DLBCL) Bone Marrow Mononuclear Cells serve as a valuable model for investigating DLBCL pathogenesis, tumor microenvironment interactions, drug resistance mechanisms, and for screening novel therapeutics. They are also applicable in immunophenotyping studies and biomarker discovery related to lymphoma progression. Moreover, they can be utilized to explore the role of epigenetic modifications in DLBCL development and therapeutic response, providing new perspectives for personalized treatment strategies.

Citation

When you publish your research, please cite our product as “AcceGen Biotech Cat.# XXX-0000”. In return, we’ll give you a $200 coupon. Simply click here and submit your paper’s PubMed ID (PMID).

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