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Human Dopaminergic Neurons (iPSC-derived, Normal)

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Home | Stem Cells | Induced Pluripotent Stem Cells (iPSCs) | Human Dopaminergic Neurons (iPSC-derived, Normal)
Species

Human
Cat.No

ABC-TC148L
Quality Control

All cells test negative for mycoplasma, bacteria, yeast, and fungi.
Product Category Stem Cells
Size/Quantity

1 vial
Cell Type

Neuron
Shipping Info

Dry Ice
Growth Conditions

37 ℃, 5% CO2
Source Organ

Brain
Disease

Normal
Biosafety Level

1
Storage

Liquid Nitrogen
Product Type

Nerve Cells

Description

Human Dopaminergic Neurons (iPSC-derived, Normal) are a type of terminally differentiated neuronal cell derived from normal human induced pluripotent stem cells (iPSCs). These cells are generated by reprogramming somatic cells using transcription factors such as Oct3/4, Sox2, Klf4, and c-Myc, followed by directed differentiation toward a midbrain dopaminergic neuron fate using specific patterning molecules including SHH (Sonic Hedgehog) and FGF8 (Fibroblast Growth Factor 8). These cells demonstrate functional dopaminergic activity, including dopamine synthesis and release in vitro. They can be used for neurodegenerative disease modeling (such as Parkinson’s disease), neurotoxicity screening, drug discovery, and stem cell research applications.

AcceGen Frozen Cells & Cell Lines 1 vial
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Application

  • Human iPSC-derived Dopaminergic Neurons are suitable for studying protein dynamics in dopaminergic neurons. Due to their complex functions, high heterogeneity, and involvement in various neural processes, these cells offer a robust in vitro model for dopaminergic neuron proteomics. Additionally, they are ideal for modeling neurodegenerative diseases such as Parkinson’s disease, helping to investigate disease pathogenesis and discover new therapeutic targets.

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