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Transfected Stable Cell Lines

Human EML4_ALK (R1275Q) BAF3 Cell Line

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Home | Transfected Stable Cell Lines | Overexpression Stable Cell Lines | Human EML4_ALK (R1275Q) BAF3 Cell Line
Species

Human
Cat.No

ABC-X0438C
Quality Control

All cells test negative for mycoplasma, bacteria, yeast, and fungi.
Product Category Transfected Stable Cell Lines
Size/Quantity

1 vial
Cell Type

Lymphocytes
Shipping Info

Dry Ice
Growth Conditions

37 °C, 5% CO2
Source Organ

Lymphatic
Disease

Normal
Biosafety Level

1
Storage

Liquid Nitrogen
Product Type

Overexpression Stable Cell Lines
Host Cell

BAF3

Description

Human EML4_ALK (R1275Q) BAF3 Cell Line is a Ba/F3 cell line expressing the EML4_ALK fusion with an R1275Q mutation, enabling IL-3–independent survival.
Target
The EML4_ALK fusion gene is found in lung cancer and results in constitutive ALK activation. The R1275Q mutation affects the kinase domain and may confer altered drug sensitivity. AcceGen offers generation of stable overexpression cell lines targeting any gene of your interest. Polyclonal or monoclonal is optional based on customers’ research needs.

AcceGen Frozen Cells & Cell Lines 1 vial
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Application

  • For research use only

  • Suitable for studying ALK-driven signaling and testing targeted inhibitors in ALK-mutant backgrounds.

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