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Transfected Stable Cell Lines

Human EML4_ALK (R1275Q) BAF3 Cell Line

  • For research use only

Cat No.

ABC-X0438C
Product Type

Overexpression Stable Cell Lines
Cell Type

Lymphocytes
Species

Human
Host Cell

BAF3
Source Organ

Lymphatic
Disease

Normal
Storage

Liquid Nitrogen

Human EML4_ALK (R1275Q) BAF3 Cell Line, EML4, ALK, Overexpression Stable Cell Lines, Transfected Stable Cell Lines

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  • Human EML4_ALK (R1275Q) BAF3 Cell Line
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Home | Transfected Stable Cell Lines | Overexpression Stable Cell Lines | Human EML4_ALK (R1275Q) BAF3 Cell Line

Description

Human EML4_ALK (R1275Q) BAF3 Cell Line is a Ba/F3 cell line expressing the EML4_ALK fusion with an R1275Q mutation, enabling IL-3–independent survival.
Target
The EML4_ALK fusion gene is found in lung cancer and results in constitutive ALK activation. The R1275Q mutation affects the kinase domain and may confer altered drug sensitivity. AcceGen offers generation of stable overexpression cell lines targeting any gene of your interest. Polyclonal or monoclonal is optional based on customers’ research needs.

Species

Human
Cat.No

ABC-X0438C
Product Category

Transfected Stable Cell Lines
Size/Quantity

1 vial
Cell Type

Lymphocytes
Growth Mode

Suspension
Shipping Info

Dry Ice
Growth Conditions

37 °C, 5% CO2
Source Organ

Lymphatic
Disease

Normal
Biosafety Level

1
Storage

Liquid Nitrogen
Product Type

Overexpression Stable Cell Lines
Host Cell

BAF3
Quality Control

All cells test negative for mycoplasma, bacteria, yeast, and fungi.

Application

  • Suitable for studying ALK-driven signaling and testing targeted inhibitors in ALK-mutant backgrounds.

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High Viability
To succeed in cell culture
Precision and Reliability
To support a consistent result
Customization Options
Tailed to your research

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