For research use only
| Cat No. | ABC-TC116L |
| Product Type | Male Reproductive Cells |
| Cell Type | Epithelial |
| Species | Human |
| Growth Conditions | 37 ℃, 5% CO2 |
| Source Organ | Epididymal |
| Disease | Normal |
| Storage | Liquid Nitrogen |
Human epididymal epithelial cells, sourced from epididymal tissue, play a key part in sperm maturation and are preserved after primary culture.
Human Epididymal Epithelial Cells are primary cells isolated from human epididymal tissue and cryopreserved after initial culture, and are often referenced in reproductive studies exploring epithelial cells in sperm, where shed epithelial components detected in semen are analyzed in relation to epididymal epithelial physiology and sperm maturation processes. These cells display cuboidal to columnar epithelial morphology with tight junctions critical for maintaining the blood-epididymis barrier. They express epithelial markers including cytokeratin and E-cadherin. Functionally, they contribute to sperm maturation, transport, and storage by regulating the epididymal microenvironment through secretion, ion transport, and immune modulation. These cells are essential for male fertility and are involved in pathologies such as epididymitis and infertility. Reflecting their physiological significance, they provide valuable in vitro models for studying epididymal biology, sperm-epithelium interactions, and male reproductive disorders. To preserve viability and functional integrity, repeated freeze-thaw cycles should be avoided during culture.
| Species | Human |
| Cat.No | ABC-TC116L |
| Product Category | Primary Cells |
| Size/Quantity | 1 vial |
| Cell Type | Epithelial |
| Growth Mode | Adherent |
| Shipping Info | Dry Ice |
| Growth Conditions | 37 ℃, 5% CO2 |
| Source Organ | Epididymal |
| Disease | Normal |
| Biosafety Level | 1 |
| Storage | Liquid Nitrogen |
| Product Type | Male Reproductive Cells |
| Quality Control | All cells test negative for mycoplasma, bacteria, yeast, and fungi. |
Human Epididymal Epithelial Cells serve as in vitro models for studying sperm maturation, epididymal function, and male reproductive health. They are useful in investigating epithelial barrier formation, ion transport mechanisms, and immune responses in the epididymis. These cells support research into male infertility causes, epididymal infections, and the effects of environmental toxins or pharmaceuticals on epididymal physiology. Co-culture models with sperm cells facilitate studies on sperm-epithelial interactions.
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These cells play a crucial role in sperm maturation, storage, and transport within the epididymis.
Yes, these cells are commonly used in research related to male fertility, sperm function, and reproductive health.
They should be cultured in epithelial cell-specific medium supplemented with growth factors and hormones.
These cells secrete factors that create an optimal environment for the final maturation of spermatozoa.