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Primary Cells

Human Epididymal Epithelial Cells

  • For research use only

Cat No.

ABC-TC116L

Product Type

Male Reproductive Cells

Cell Type

Epithelial

Species

Human

Growth Conditions

37 ℃, 5% CO2

Source Organ

Epididymal

Disease

Normal

Storage

Liquid Nitrogen

Human epididymal epithelial cells, sourced from epididymal tissue, play a key part in sperm maturation and are preserved after primary culture.

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Description

Human Epididymal Epithelial Cells are primary cells isolated from human epididymal tissue and cryopreserved after initial culture, and are often referenced in reproductive studies exploring epithelial cells in sperm, where shed epithelial components detected in semen are analyzed in relation to epididymal epithelial physiology and sperm maturation processes. These cells display cuboidal to columnar epithelial morphology with tight junctions critical for maintaining the blood-epididymis barrier. They express epithelial markers including cytokeratin and E-cadherin. Functionally, they contribute to sperm maturation, transport, and storage by regulating the epididymal microenvironment through secretion, ion transport, and immune modulation. These cells are essential for male fertility and are involved in pathologies such as epididymitis and infertility. Reflecting their physiological significance, they provide valuable in vitro models for studying epididymal biology, sperm-epithelium interactions, and male reproductive disorders. To preserve viability and functional integrity, repeated freeze-thaw cycles should be avoided during culture.

Species

Human

Cat.No

ABC-TC116L

Product Category

Primary Cells

Size/Quantity

1 vial

Cell Type

Epithelial

Growth Mode

Adherent

Shipping Info

Dry Ice

Growth Conditions

37 ℃, 5% CO2

Source Organ

Epididymal

Disease

Normal

Biosafety Level

1

Storage

Liquid Nitrogen

Product Type

Male Reproductive Cells

Quality Control

All cells test negative for mycoplasma, bacteria, yeast, and fungi.

Application

  • Human Epididymal Epithelial Cells serve as in vitro models for studying sperm maturation, epididymal function, and male reproductive health. They are useful in investigating epithelial barrier formation, ion transport mechanisms, and immune responses in the epididymis. These cells support research into male infertility causes, epididymal infections, and the effects of environmental toxins or pharmaceuticals on epididymal physiology. Co-culture models with sperm cells facilitate studies on sperm-epithelial interactions.

Citation

When you publish your research, please cite our product as “AcceGen Biotech Cat.# XXX-0000”. In return, we’ll give you a $200 coupon. Simply click here and submit your paper’s PubMed ID (PMID).

Frequently Asked Questions

  • What is the primary function of Human Epididymal Epithelial Cells in the male reproductive system?

    These cells play a crucial role in sperm maturation, storage, and transport within the epididymis.

  • Can Human Epididymal Epithelial Cells be used for studying male fertility and reproductive disorders?

    Yes, these cells are commonly used in research related to male fertility, sperm function, and reproductive health.

  • What culture conditions are required for optimal growth of Human Epididymal Epithelial Cells?

    They should be cultured in epithelial cell-specific medium supplemented with growth factors and hormones.

  • How do Human Epididymal Epithelial Cells contribute to sperm maturation?

    These cells secrete factors that create an optimal environment for the final maturation of spermatozoa.

Inquiring Human Epididymal Epithelial Cells

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High Viability
To succeed in cell culture
Precision and Reliability
To support a consistent result
Customization Options
Tailed to your research

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