For research use only
| Cat No. | ABC-GF0022 |
| Product Type | Others |
Erythropoietin is a glycosylated cytokine that regulates red blood cell production, erythroid differentiation, hemoglobin synthesis, and protects tissues.
Erythropoietin (EPO) is a secreted, glycosylated cytokine composed of four alpha-helical bundles. EPO can be found in the plasma and regulates red cell production by promoting erythroid differentiation and initiating hemoglobin synthesis. It also has neuroprotective activity against a variety of potential brain injuries and antiapoptotic functions in several tissue types. EPO is the principal hormone involved in the regulation of erythrocyte differentiation and the maintenance of a physiological level of circulating erythrocyte mass. It is produced by kidney or liver of adult mammals and by liver of fetal or neonatal mammals. Genetic variations in EPO are associated with susceptibility to microvascular complications in type 2 diabetes.
| Species | Human |
| Cat.No | ABC-GF0022 |
| Product Category | Cell Culture Media, kits & Reagents |
| Size/Quantity | 20 µg/100 µg/1 mg |
| Shipping Info | In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. |
| Storage | -20°C |
| Product Type | Others |
| Concentration | ≥ 95 % as determined by SDS-PAGE and SEC-HPLC. |
| Key Features | < 10 EU per mg protein |
EPO stimulates cell proliferation in the TF-1 human erythroleukemic cell line in a dose-dependent manner. They include diabetic retinopathy, diabetic nephropathy leading to end-stage renal disease, and diabetic neuropathy.