+1 862-686-2696
Featured Products
Primary Cells
Immortalized Cell Lines
Stem Cells
Tumor Cell Lines
Transfected Stable Cell Lines
Exosomes
MicroRNA Agomir/Antagomir
Nucleic Acid Kits
Explore Products
Cell
Cell
MicroRNA
MicroRNA
Test and Analysis
Test and Analysis
Transfected Stable Cell Lines

Human ERBB2 (D769Y) BAF3 Cell Line

  • BSL

    1

  • 92
Request Your Custom Quote Today

Discover top-quality products tailored for scientific and medical research. Request a personalized quote today
to enhance your projects.

Get a Quote
  • High Purity Levels
  • Precision and Reliability
  • Customization Options
Home | Transfected Stable Cell Lines | Overexpression Stable Cell Lines | Human ERBB2 (D769Y) BAF3 Cell Line
Species

Human
Cat.No

ABC-X0353C
Quality Control

All cells test negative for mycoplasma, bacteria, yeast, and fungi.
Product Category Transfected Stable Cell Lines
Size/Quantity

1 vial
Cell Type

Lymphocytes
Shipping Info

Dry Ice
Growth Conditions

37 °C, 5% CO2
Source Organ

Lymphatic
Disease

Normal
Biosafety Level

1
Storage

Liquid Nitrogen
Product Type

Overexpression Stable Cell Lines
Host Cell

BAF3

Description

Human ERBB2 (D769Y) BAF3 Overexpression Cell Line is a genetically engineered model developed from murine BAF3 pro-B cells based on customers’ requirement. This cell line stably expresses the human ERBB2 (HER2) gene with the D769Y mutation introduced through lentiviral transduction. Gene expression is validated by qRT-PCR and the cells are maintained under low passage (<P20). Target ERBB2 (HER2) encodes a receptor tyrosine kinase overexpressed or mutated in breast, gastric, and lung cancers. The D769Y mutation is located in the kinase domain and enhances constitutive signaling, promoting cell proliferation and therapeutic resistance. AcceGen offers generation of stable overexpression cell lines targeting any gene of your interest. Polyclonal or monoclonal is optional based on customers’ research needs.

AcceGen Frozen Cells & Cell Lines 1 vial
View Product Image

Application

  • For research use only

  • This cell model expresses the oncogenic D769Y mutant of ERBB2 (HER2), a variant associated with constitutive kinase activation in breast and gastric cancers. It enables functional studies of HER2 signaling, drug screening for HER2-targeted therapies, and analysis of downstream pathways like PI3K-AKT and MAPK. The cell line is widely used to evaluate therapeutic sensitivity and resistance mechanisms involving ERBB2 mutations.

  • Online Inquiry
  • Product Reviews

Inquiring Human ERBB2 (D769Y) BAF3 Cell Line

We know how valuable your research is to you, but are you wondering what you can expect to pay for quick accurate results every time? Fill out a request in the form below and we’ll get back to you within 24 hours with a quote.
High Viability
To succeed in cell culture
Precision and Reliability
To support a consistent result
Customization Options
Tailed to your research

Tags

Let's Advance Life Science Research Together

Contact Us
AcceGen Scroll Top Button