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Human ERBB2 (D769Y) BAF3 Cell Line

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Home | Transfected Stable Cell Lines | Overexpression Stable Cell Lines | Human ERBB2 (D769Y) BAF3 Cell Line
Species

Human
Cat.No

ABC-X0353C
Quality Control

All cells test negative for mycoplasma, bacteria, yeast, and fungi.
Product Category Transfected Stable Cell Lines
Size/Quantity

1 vial
Cell Type

Lymphocytes
Shipping Info

Dry Ice
Growth Conditions

37 °C, 5% CO2
Source Organ

Lymphatic
Disease

Normal
Biosafety Level

1
Storage

Liquid Nitrogen
Product Type

Overexpression Stable Cell Lines
Host Cell

BAF3

Description

Human ERBB2 (D769Y) BAF3 Overexpression Cell Line is a genetically engineered model developed from murine BAF3 pro-B cells based on customers’ requirement. This cell line stably expresses the human ERBB2 (HER2) gene with the D769Y mutation introduced through lentiviral transduction. Gene expression is validated by qRT-PCR and the cells are maintained under low passage (

AcceGen Frozen Cells & Cell Lines 1 vial
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Application

  • For research use only

  • This cell model expresses the oncogenic D769Y mutant of ERBB2 (HER2), a variant associated with constitutive kinase activation in breast and gastric cancers. It enables functional studies of HER2 signaling, drug screening for HER2-targeted therapies, and analysis of downstream pathways like PI3K-AKT and MAPK. The cell line is widely used to evaluate therapeutic sensitivity and resistance mechanisms involving ERBB2 mutations.

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