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Transfected Stable Cell Lines

Human ERBB2 (L786V) BAF3 Cell Line

  • For research use only

Cat No.

ABC-X0265C
Product Type

Overexpression Stable Cell Lines
Cell Type

Lymphocytes
Species

Human
Host Cell

BAF3
Source Organ

Lymphatic
Disease

Normal
Storage

Liquid Nitrogen

Human ERBB2 (L786V) BAF3 Cell Line serves as a valuable model to examine HER2 mutation-driven cancer progression and targeted drug responses.

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  • Human ERBB2 (L786V) BAF3 Cell Line
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Home | Transfected Stable Cell Lines | Overexpression Stable Cell Lines | Human ERBB2 (L786V) BAF3 Cell Line

Description

Human ERBB2 (L786V) BAF3 Cell Line is a genetically modified BAF3 cell line designed to stably express the ERBB2 oncogene harboring the L786V mutation. Integration is performed using lentiviral vectors and validated by qRT-PCR. Edited cells are maintained under low passage (<P20). Target ERBB2 (HER2) encodes a receptor tyrosine kinase involved in cell proliferation and survival. The L786V mutation enhances kinase activity and has been linked to therapeutic resistance in HER2-positive cancers. AcceGen offers generation of stable overexpression cell lines targeting any gene of your interest. Polyclonal or monoclonal is optional based on customers' research needs.

Species

Human
Cat.No

ABC-X0265C
Product Category

Transfected Stable Cell Lines
Size/Quantity

1 vial
Cell Type

Lymphocytes
Growth Mode

Suspension
Shipping Info

Dry Ice
Growth Conditions

37 °C, 5% CO2
Source Organ

Lymphatic
Disease

Normal
Biosafety Level

1
Storage

Liquid Nitrogen
Product Type

Overexpression Stable Cell Lines
Host Cell

BAF3
Quality Control

All cells test negative for mycoplasma, bacteria, yeast, and fungi.

Application

  • This model enables study of HER2-driven oncogenic signaling, with applications in resistance mechanism profiling and efficacy testing of HER2-targeted therapies.

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High Viability
To succeed in cell culture
Precision and Reliability
To support a consistent result
Customization Options
Tailed to your research

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