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Transfected Stable Cell Lines

Human ERBB2 (L786V) BAF3 Cell Line

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Home | Transfected Stable Cell Lines | Overexpression Stable Cell Lines | Human ERBB2 (L786V) BAF3 Cell Line
Species

Human
Cat.No

ABC-X0265C
Quality Control

All cells test negative for mycoplasma, bacteria, yeast, and fungi.
Product Category Transfected Stable Cell Lines
Size/Quantity

1 vial
Cell Type

Lymphocytes
Shipping Info

Dry Ice
Growth Conditions

37 °C, 5% CO2
Source Organ

Lymphatic
Disease

Normal
Biosafety Level

1
Storage

Liquid Nitrogen
Product Type

Overexpression Stable Cell Lines
Host Cell

BAF3

Description

Human ERBB2 (L786V) BAF3 Cell Line is a genetically modified BAF3 cell line designed to stably express the ERBB2 oncogene harboring the L786V mutation. Integration is performed using lentiviral vectors and validated by qRT-PCR. Edited cells are maintained under low passage (<P20). Target ERBB2 (HER2) encodes a receptor tyrosine kinase involved in cell proliferation and survival. The L786V mutation enhances kinase activity and has been linked to therapeutic resistance in HER2-positive cancers. AcceGen offers generation of stable overexpression cell lines targeting any gene of your interest. Polyclonal or monoclonal is optional based on customers' research needs.

AcceGen Frozen Cells & Cell Lines 1 vial
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Application

  • For research use only

  • This model enables study of HER2-driven oncogenic signaling, with applications in resistance mechanism profiling and efficacy testing of HER2-targeted therapies.

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